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XELOX化疗方案对胃癌患者免疫功能与治疗疗效的影响 被引量:6

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摘要 目的:探讨XELOX化疗方案对胃癌患者免疫功能与治疗疗效的影响。方法:将胃癌化疗患者40例根据化疗方法的不同分为治疗组与对照组各20例,治疗组给予XELOX化疗方案,对照组给予OLF方案治疗。结果:治疗组与对照组的有效率分别为55.0%和50.0%,两组对比,差异无统计学意义(P>0.05)。两组患者CD3+、CD4+值于化疗2 d和化疗后显著降低(P<0.05),同时两组对比,差异有统计学意义(P<0.05)。两组CD8+值在各时间对比,差异均无统计学意义(P>0.05)。结论:XELOX化疗方案应用于胃癌治疗能在保持治疗疗效的基础上,对T淋巴细胞亚群有保护作用,从而有利于患者机体的免疫功能的恢复,值得推广应用。
作者 华萍
出处 《吉林医学》 CAS 2012年第26期5687-5687,共1页 Jilin Medical Journal
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  • 1Schuhmacher CP,Fink U,Becker K,et al.Neoadjuvant therapy for patients with locally advanced gastric carcinoma with etoposide,doxorubicin,and cisplatinum.Closing results after 5 years of follow-up[J].Cancer,2001,91(5):918-927. 被引量:1
  • 2Webb A,Cunningham D,Scarffe JH,et al.Rancomized trial comparing epirubicin,ciaplatin,and fluorouracil versus fluorouracil,doxorubicin,and methotrexate in advaced espohagogastric cancer[J].J Clin Oncol,1997,15(1):261-267. 被引量:1
  • 3Ajani JA,Fodor M,Van Cutsem E,et al.Multinational randomized trial of docetaxel,cosplatin with or without 5-fluorouracil in patients with advanced gastric or GE junction adenocarcinoma[J].Proc Am Soc Clin Oncol,2000,36th annual meeting:957 abstract. 被引量:1
  • 4Honecker F,Kollmannsberger C,Quietzsch D,et al.Phase Ⅱ study of weekly paclitaxel plus 24-h continuous infusion 5-fluorouracil,folinic acid and 3-weekly cisplatin for the treatment of patients with advanced gastric cancer[J].Anticancer Drugs,2002,13(5):4 被引量:1
  • 5Macdonald JS.Adjuvant therapy for gastric cancer[J].Semin Oncol,2003,30(11):19-25. 被引量:1
  • 6Macdonald JS,Smalley SR,Benedetti J,et al.Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction[J].N Engl J Med,2001,345(10):725-730. 被引量:1
  • 7Kettner E,Ridwelski K,Keiholz U,et al.Docetaxel and cisplatin combination chemotherapy for advanced gastric cancer.Results of two phase Ⅱ studies[J].Proc Am Soc Clin Oncol,2001,37th annual meeting:657abstract. 被引量:1
  • 8Ajani JA,Baker J,Pisters PW,et al.CPT-11 plus cisplatin in patients with advanced,untreated gastric ogastroesophageal junction carcinoma:results of a phase Ⅱ study[J].Cancer,2002,94(3):641-646. 被引量:1
  • 9Kim TW,Kang YK,Ahn JH,et al.Phase Ⅱ study of capecitabine plus cisplatin as first-line chemotherapy in advanced gastric cancer[J].Ann Oncol,2002,13(12):1893-1898. 被引量:1
  • 10金懋林,陈强,程凤歧,陈伟,陈黎,潘良熹,杨宇飞.奥沙利铂联合亚叶酸钙和5-氟尿嘧啶治疗晚期胃癌的研究[J].中华肿瘤杂志,2003,25(2):172-174. 被引量:404

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