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全凭静脉麻醉在腹腔镜胆囊切除术的应用观察 被引量:2

Clinical Observation on Laparoscopic Cholecystectomy by Total Intravenous Anesthesia
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摘要 目的探讨瑞芬太尼复合丙泊酚全凭静脉麻醉与静吸复合麻醉在腹腔镜胆囊切除术(LC)中的有效性和安全性。方法择期LC手术60例,随机分为全凭静脉麻醉组(A组)静吸复合麻醉组(B组),每组30例。两组均以咪达唑仑0.1 mg/kg、丙泊酚2 mg/kg、瑞芬太尼2μg/kg、维库溴铵0.1 mg/kg诱导后气管插管。麻醉维持B组用2%异氟醚吸入,A组每分钟丙泊酚6 mg/kg和瑞芬太尼0.5μg/kg的速度用微量泵输入。记录麻醉诱导前、气腹前和气腹后5 min和术毕的收缩压(SBP)、舒张压(DBP)、心率(HR)、血氧饱和度(SPO2)、唤醒时间、拔管时间和清醒程度及不良反应。结果两组患者拔管时间和清醒程度均无显著性差异;A组镇静评分(OAAS评分)明显高于B组(P<0.05);B组在气腹后5 min的HR、SBP、DBP及气腹后5 min、气腹结束、术毕的HR显著高于麻醉诱导前的基础值(P<0.05),A组术中无明显变化;气腹后5 min、气腹结束及术毕B组的HR和SBP均明显高于A组(P<0.05);气腹后5 min、气腹结束时B组的DBP明显高于A组(P<0.05);A组的术后恶心呕吐发生率显著低于B组(P<0.05)。结论与常规静吸复合麻醉下行LC手术比较,丙泊酚复合瑞芬太尼全凭静脉麻醉围手术期麻醉更平稳,并发症较少。
出处 《河南科技大学学报(医学版)》 2012年第3期216-217,共2页 Journal of Henan University of Science & Technology:Medical Science
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