摘要
目的观察阿托伐他汀治疗糖尿病早期肾病的疗效。方法选择我院2008年—2010年住院的糖尿病早期肾病患者48例,随机分为治疗组和对照组,各24例。比较两组患者治疗前及治疗6个月后的血生化指标及药物不良反应。结果治疗后治疗组尿微量清蛋白、血肌酐、超敏C反应蛋白与对照组比较,差异均有统计学意义(P<0.05)。结论阿托伐他汀能降低糖尿病早期肾病患者的尿微量清蛋白、超敏C反应蛋白,改善肾功能。
Objective To observation of the effects of atorvastatin in the treatment of early diabetic nephropathy. Methods Our hospital foom 2008 to 2010 in hospitalized diabetic patients with early diabetic nephropathy 48 eases, were ran- domly divided into treatment group and control group, 24 cases in each. Comparison of the two groups before treatment and after treatment for 6 months, blood biochemical index and adverse drug reaction. Results After treatment, the treatment groupuri- nary albumin, serum ereatinine, high sensitivity C reactive protein in comparison with the control group, the difference was sta- tistically significant (P 〈0. 05). Conclusion Atorvastatin reduced the early diabetic nephropathy patients with microalbumin- uria, high sensitivity C reactive protein, improve renal function.
出处
《实用心脑肺血管病杂志》
2012年第10期1660-1660,1662,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
糖尿病肾病
阿托伐他汀
治疗结果
Diabetic nephropathy
Atorvastatin
Treatment outcome