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基于HIS灯盏细辛注射液“真实世界”临床用药特点分析 被引量:68

Dengzhanxixin injection using character analysis in clinical based on real world HIS database
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摘要 目的:了解灯盏细辛注射液的临床应用情况,为规范临床合理用药及前瞻性研究提供思路与指导。方法:选取全国20家三甲综合医院使用灯盏细辛注射液的住院患者信息,运用基本数据描述方法及关联规则进行分析。结果:在21 498例患者中,用药患者多为45岁以上老年人;主要用于脑梗死(中医诊断为中风)、冠心病、高血压病、糖尿病的治疗;用法以静脉注射为主,单次用药剂量多集中在30~40 mL;用药疗程多为14 d左右。结论:灯盏细辛注射液临床使用基本符合药品说明书;患者多为老年患者,且多合并有糖尿病和高血压病。 Objective: To know the truth how does Dengzhanxixin injection be used in clinical practice, and to regulate clinical use, and to direct the prospective study design. Method: Twenty comprehensive hospital information system (HIS) data are collected. Cleaning up the database, then analysis the patients' information which the patients have used Dengzhanxixin injection. Using the basic description method and association rules to analysis the data. Result: By analysis the Dengzhanxixin data come from HIS database we found that the most patient's age are elder than 45, it was used to treat ischemie stroke, coronary heart disease, diabetes and hypertension. It is always used in the form of intravenous injection, and are always used in 30-40 mL dosage in clinical practice ,and it is always used for 14 days for one time. Conclusion: The patients are usually used in old people. And the injection's using in clinical are mostly complied with the instructions. The patients who had been used Dengzhanxixin injection usually have diabetes and hyperten-
出处 《中国中药杂志》 CAS CSCD 北大核心 2012年第18期2718-2722,共5页 China Journal of Chinese Materia Medica
基金 国家"重大新药创制"科技重大专项(2009ZX09502-030)"中药上市后评价关键技术研究"
关键词 灯盏细辛注射液 真实世界 医院信息系统 临床用药特点 描述分析 实效研究 Dengzhanxixin injection real world hospital information system drug using character descriptive analysis out-comes research
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