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缺血后处理对急性ST段抬高型心肌梗死不同病变血管再灌注损伤的影响 被引量:2

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摘要 目的:探讨缺血后处理对急性ST段抬高型心肌梗死(STEMI)不同病变血管再灌注损伤的影响。方法:选择在12h内行经皮冠状动脉介入治疗的STEMI患者为研究对象,分为对照组(n=26)和缺血后处理组(n=83)。其中缺血后处理组分为3组:单支病变组26例,双支病变组29例,三支病变组28例。对照组采用再灌注治疗;缺血后处理组采用再灌注30s、再缺血20s,交替3次后再持续灌注治疗。比较两组实验对心肌不同病变血管再灌注损伤的影响。结果:缺血后处理组中单支病变组和双支病变组的再灌注心律失常发生率明显低于三支病变组和对照组(P<0.05);缺血后处理组中单支病变组和双支病变组的CTFC、WMSI、QRS-MIS均低于三支病变组和对照组(P<0.05);LVEF明显高于三支病变组和对照组(P<0.05)。结论:心肌缺血后处理能显著减轻单支病变和双支病变的STEMI患者心肌再灌注的损伤,具有显著的保护作用。
出处 《实用医学杂志》 CAS 北大核心 2012年第19期3245-3247,共3页 The Journal of Practical Medicine
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