摘要
【目的】探讨影响老年直肠癌患者预后的临床及病理相关危险因素。【方法】对本院收治的老年直肠癌患者300例的病例资料进行回顾性分析。【结果】①单因素分析显示，根据癌变部位、肿瘤长度分组的患者之间生存率相比差异无统计学意义（P〉0．05），根据症状持续时间、术前癌胚抗原（CEA）水平、病理分型、浸润程度、治疗方式、淋巴结转移、临床分期、病理分级分组的患者之间生存率相比差异有统计学意义（P〈0．05）。②多因素分析显示，术前CEA水平、浸润程度、治疗方式是影响患者治疗预后的独立危险因素（P〈0．05）。【结论】影响老年直肠癌患者预后的独立危险因素有术前CEA水平、浸润程度、治疗方式。
[Objective]To investigate the clinical and pathological risk factors affecting the prognosis of elderly patients with rectal cancer. [Methods] Clinical data of 300 elderly patients with rectal cancer admitted to our hos pital were analyzed retrospectively. [Results]Univariate analysis showed that there was no significant difference in survival rate among patients grouped by cancer site and tumor length （ P 0. 05）, while there were significant differences in survival rate among patients grouped by duration of symptoms, preoperative level of CEA, patholog ical type, degree of infiltration, treatment method, lymph node metastasis, clinical stage and histological grade be tween groups（ P %0.05）. Multivariate analysis showed that preoperative level of CEA, degree of infiltration and treatment method were the independent risk factors affecting the prognosis of patients（ P %0.05）. [Conclusion] The independent risk factors affecting the prognosis of elderly patients with rectal cancer include preoperative level of CEA, infiltration degree and treatment method.
出处
《医学临床研究》
CAS
2012年第8期1537-1539,共3页
Journal of Clinical Research
