期刊文献+

循环肿瘤细胞的检测和临床应用的认识 被引量:1

原文传递
导出
摘要 恶性肿瘤的转移是导致患者死亡的主要原因之一。肿瘤的侵袭和转移可在肿瘤发生早期就已出现,故检测肿瘤的微转移是长期以来检验医学所面临的挑战之一。循环肿瘤细胞(circulating tumor cell,CTC)在肿瘤转移过程中发挥了重要作用,而CTC检测技术的出现,使人们对肿瘤转移的监测达到了单细胞水平,成为肿瘤的"液态活检"。
出处 《诊断学理论与实践》 2012年第4期325-328,共4页 Journal of Diagnostics Concepts & Practice
  • 相关文献

参考文献15

  • 1Pantel K, Brakenhoff RH, Brandt B. Detection, clinical relevance and specific biological properties of dissemina- ting tumour cells[J]. Nat Rev Cancer,2008,8(5):329-340. 被引量:1
  • 2Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis[J]. Science,2011,331(6024):1559-1564. 被引量:1
  • 3Joyce JA, Pollard JW. Microenvironmental regulation of metastasis[J]. Nat Rev Cancer,2009,9(4):239-252. 被引量:1
  • 4Lianidou ES, Markou A. Circulating tumor cells in breast cancer: detection systems, molecular characterization, and future challenges[J]. Clin Chem,2011,57(9): 1242-1255. 被引量:1
  • 5Cristofanilli M, Budd GT, Ellis MJ, et al. Circulating tu-mor cells, disease progression, and survival in metastatic breast cancerp[J]. N Engl J Med,2004,351(8):781-791. 被引量:1
  • 6Hou JM, Krebs MG, Lancashire L, et al. Clinical signifi- cance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer[J]. J Clin Oncol,2012,30(5):525-532. 被引量:1
  • 7Cohen SJ, Punt C J, Iannotti N, et al. Relationship of cir- culating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic coloreetal cancer[J]. J Clin Oncol,2008,26(19):3213-3221. 被引量:1
  • 8Punnoose EA, Atwal S, Liu W, et al. Evaluation of circu- lating tumor cells and circulating tumor DNA in non-small cell lung cancer: association with clinical endpoints in a phase Ⅱ clinical trial of pertuzumab and erlotinib[J]. Clin Cancer Res,2012,18(8):2391-2401. 被引量:1
  • 9Riethdorf S, Muller V, Zhang L, et al. Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoad- juvant GeparQuattro trial[J]. Clin Cancer Res,2010,16(9): 2634-2645. 被引量:1
  • 10Hughes AD, Mattison J, Western LT, et al. Microtube de- vice for seleetin-mediated capture of viable circulating tu- mor cells from blood[J]. Clin Chem,2012,58(5):846-853. 被引量:1

同被引文献27

  • 1黄同海,王正,李富荣.循环肿瘤细胞检测的研究新进展[J].中国肿瘤临床,2007,34(8):476-479. 被引量:15
  • 2Mavroudis D. Circulating cancer cells[J].{H}ANNALS OF ONCOLOGY,2010,(SUPPL.7):i95-i100. 被引量:1
  • 3Chaffer CL,Weinberg RA. A perspective on cancer cell metastasis[J].{H}SCIENCE,2011,(6024):1559-1564. 被引量:1
  • 4Joyce JA,Pollard JW. Microenvironmental regulation of metastasis[J].{H}Nature Reviews Cancer,2009,(04):239-252. 被引量:1
  • 5Jiang W,Zhang H. Enrichment and detection of Circulating cancer cells inperipheral blood[J].Chin-Ger J Clin oncol,2011,(04):24-244. 被引量:1
  • 6Cohen SJ,Punt CJ,Iannotti N. Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer[J].{H}ANNALS OF ONCOLOGY,2009,(07):1223-1229. 被引量:1
  • 7Goodale D,Phay C,Postenka CO. Characterization of tumor cell dissemination patterns in preclinical models of cancer metastasis using flow cytometry and laser scanning cytometry[J].Cytometry A,2009.344-355. 被引量:1
  • 8Carcia JA,Rosenberg JE,Weinberg V. Evaluation and significance of circulating epithelial cells in patients with hormone-refractory prostate cancer[J].{H}BJU International,2007,(03):519-524. 被引量:1
  • 9Hoeppener AE,Swennenhuis JF,Terstappen LW. Immunomagnetic separation technologies[J].{H}Recent Results in Cancer Research,2012,(12):43-48. 被引量:1
  • 10Pachmannk K,Clement JH,Schneider CP. Standardized quantification of circulating peripheral tumor cells from lung and breast cancer[J].{H}Clinical Chemistry and Laboratory Medicine,2005,(06):617-627. 被引量:1

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部