摘要
目的分析并探讨肾黏液管状梭形细胞癌的临床特征。方法对1例左肾黏液管状梭形细胞癌病例的临床资料进行回顾性分析,其由于出现不明原因发热等症状住院就诊,进行根治性肾癌切除术,肿瘤大小约100mm×70mm,临床分期为T2N0M0,其病理表现为排列成簇的狭长小管状上皮细胞,中间充满黏液间质和梭形细胞,免疫标记示Vimentin(++)、p504S(++)、CD10(-)、CK7(-)、Villin(-)、E-cad(-)。结果术后1d体温基本恢复正常,术后1年随访出现胸12椎体转移,第3年死亡。结论肾黏液管状梭形细胞癌属于低度恶性肾上皮性肿瘤,免疫组化分析其可能来源于远端肾小管,可出现神经内分泌分化,早期采用手术切除可取得较好的预后。
Objective To analyze and discuss the clinical features of renal tubular mucus spindle cell carcinoma. Methods 1 patients with left renal mucus tubular spindle cell carcinoma of the clinical data were retrospectively analyzed, The patientcame to the hospital with fever of undetermined origin. The size of thetumorwas 100mm×70mm. Clinical stage：T2NOM0. Histologic feature： tumors consisted of tightly packed,small,elongated tubules separated by pale mucinousstrom.The tumor cells were cuboidal to spindled with eosinophiliccytoplasm.The Immunohistochemical staining of the tumor is Vimentin（＋＋）,p504S（＋＋）,CD10（-）,CK7（-）,Villin（-）,E-cad（-）. Results After one day temperature basic back to normal, after one year follow-up appear bosom 12 vertebral transfer, the third year death. Conclusion The kidney mucous tubular spindle cells is a kind of cancer low-grade malignant renal epithelial neoplasm, immunohistochemistry analysis may originate from the distal renal tubular, can appear neuroendocrine differentiation, early surgery treatment can acquire better prognosis.
出处
《当代医学》
2012年第28期104-105,共2页
Contemporary Medicine
关键词
肾肿瘤
黏液性管状梭形细胞癌
临床特征
Renal tumor
Mucous sex tubular spindle cell carcinoma
Clinical features
