摘要
目的:通过分析川崎病的流行病学特征及临床特点,为川崎病早期诊断及治疗提供临床依据。方法:对广州市越秀区儿童医院2007年至2011年诊治的34例川崎病患儿进行回顾性分析和总结。结果:(1)34例川崎病患儿中男23例,女11例,男女比例为2∶1;发病年龄以3岁以内婴幼儿为主(88.2%);发病季节以春、秋为主;不完全川崎病17例(50.0%)。发热率100%,确诊前平均发热时间为6.5 d,其他临床表现依次为口唇病变(83.4%)、球结膜充血(70.6%)、肢端硬肿或脱皮(64.7%)、皮疹(52.9%)、淋巴结肿大(35.3%)。(2)心血管病变:合并冠状动脉病变者27例(79.4%),未见有冠状动脉瘤。(3)其他系统并发症:支气管炎、急性胃肠炎、口腔溃疡等。结论:川崎病具有多系统、多器官受累特点,冠状动脉病变发生与血沉(ESR)、C反应蛋白(CRP)、血小板(PLT)升高有关,不完全川崎病发病率高。
To investigate the epidemic features, clinical features of Kawasaki disease in the Children＇s Hospital of Guangzhou, in order to promote early diagnosis and treatment. Methods： The clinical characteristics and treatment of 34 cases with Kawasaki disease from 2007 to 2011 were analyzed retrospectively and summarized. Results： （ 1 ） Clinical features： male to female ratio was 2 ： 1. The peak age of onset was 0 - 3 years （88.2%）. The peak onset time was the Spring and Autumn. The 17 cases （50. 0% ） were incomplete KD. The 34 cases all had fever （ 100% ）. The average duration of fever before diagnosing was 6.5 days, 83.4% had oral mucosa erythema and dry, fissured lips and/or strawberry tongue, 70. 6% had bilateral conjunctival congestion, 64.7% had redness and/or swelling/or desquamation of the hands and feet, 52.9% had rash, 35.3% had cervical lymphadenopathy of at least 1.5 cm in diameter. （2） Coronary artery damage： coronary artery damage existed in 27 cases （79.4%）, no one had coronary aneurysm formation. （3） Non-cardiovascular complications ： bronchitis, acute gastroenteritis, canker sore, et al. Conclusions： KD could cause the breakdown of all kinds of systems. The occurrence of coronary artery is related to ESR, CRP, PLT. Incomplete KD has a high incidence.
出处
《儿科药学杂志》
CAS
2012年第9期10-12,共3页
Journal of Pediatric Pharmacy
基金
广州市越秀区科技计划项目
编号2011-WS-030
关键词
川崎病
冠状动脉损害
临床分析
Kawasaki disease
Coronary arterial lesion
Clinical characteristics
