摘要
目的:了解用中西医结合方法治疗乙型肝炎后肝硬化腹水的临床效果。方法:将160例乙肝后肝硬化腹水患者,随机分为两组,对照组给予常规西医治疗,治疗组在常规西医治疗基础上,给予益气疏肝活血的中药汤剂,3个月后观察并比较两组患者的临床症状与体征、肝功能、肝纤维化程度以及临床总有效率。结果:与对照组比较,治疗组患者纳差、腹胀、浮肿等临床症状改善更快(P<0.05);治疗组患者丙氨酸转氨酶(ALT)、凝血酶原时间(PT)和总胆红素(TBil)水平明显低于对照组(P<0.05);治疗组患者肝纤维化指标明显低于对照组(P<0.05);治疗组患者腹围[(79.1±6.47)cm]明显小于对照组[(91.6±4.1)cm](P<0.05);治疗组总有效率90.0%,对照组总有效率68.8%,两组差异明显(P<0.05)。结论:中西医结合治疗乙肝后肝硬化腹水临床效果显著,可明显改善患者的临床症状,肝功能、改善纤维化指标,临床总有效率明显高于单纯西药治疗。
Objective：To study the clinical effect of traditional Chinese medicine combined with western medicine in treatment of liver cirrhosis ascites.Method：One handred and sixty patients with liver cirrhosis ascites from Mar,2009 to Sep,2011 were randomly divided into treatment group and control group.The patients in control group were treated with westeren medicine,the patients in treatment group was received with traditional Chinese medicine combined with western medicine.Three month after,clinical symptom,liver function,liver fibrosis and total effective ratio were compared.Result：After 3 months,the clinical symptom of treatment group was improved faster than that in control group（P〈0.05）;the functional marker of liver in treatment group was lower than that in control group（P〈0.05）.And liver fibrosis in treatment group was much optimistic than control group.And the abdominal circumference was less than control group（P〈0.05）;the total effective rate of treatment group was 90.0%,and the rate of control group was 68.8%（P〈0.05）.Conclusion：Traditional Chinese medicine combined with western medicine showed satisfactory clinical efficacy in the treatment of liver cirrhosis ascites.It improved clinical symptom significantly,live function and fibrosis of patients in treatment group were better those in than control group.and it was worthy of clinical use.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第18期275-277,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
中医药
肝硬化
腹水
临床观察
traditional Chinese medicine； liver cirrhosis； ascites； clinical observation
