摘要
目的探讨咪唑安定、芬太尼联合布比卡因用于妇产科术后硬膜外自控镇痛(PCEA)的临床效果观察。方法对我院2008-11—2012-03收治的ASAI～Ⅱ级采用连续硬膜外麻醉且术后采用PCEA镇痛的病人78例,随机分为观察组和对照组各39例,观察组应用咪唑安定、芬太尼联合布比卡因进行镇痛;对照组应用芬太尼和布比卡因进行镇痛。分别观察2组患者的镇痛效果、疼痛评分、生命体征及不良反应。结果观察组优良率为97.43%,明显高于对照组的69.23%,2组镇痛,比较差异有统计学意义(P<0.05)。观察组中恶心呕吐3例,皮肤瘙痒2例;对照组中恶心呕吐4例,皮肤瘙痒1例,2组间比较差异无统计学意义(P>0.05),2组中均无尿潴留及呼吸抑制的发生。结论眯唑安定、芬太尼复合布比卡因用于妇产科术后是安全有效的,且不良反应轻微,值得临床推广应用。
Objective To investigate clinical effect the midazolam, fentanyl combined with bupivacaine for obstetrics and gynecology postoperative patient-controlled epidural analgesia （PCEA）. Methods Our hospital in November 2008 to March 2012 January ASA Ⅲ level with continuous epidural anesthesia and postoperative PCEA analgesia in patients 78 cases were randomly divided into observation group and control group, each group of 39 cases. Observation group used midazolam, fenta- nyl combined with bupivacaine analgesia; fentanyl and bupivacaine for analgesia in the control group. The analgesic effect of the two groups of patients, pain scores, vital signs and adverse reactions were observed. Results The good rate in observation group was 97.43 %, which was significantly higher than that in control group（69.23 %）, the difference of analgesic was significant between the two groups （P〈0.05）. Three cases of nausea and vomiting in the observation group,itchy skin in 2 cases, 4 cases of nausea and vomiting in the control group, skin itching in 1 cases, there was no significant difference （P〈0.05） between the two groups. Patients in the two groups had no urinary retention and respiratory depression. Conclusion Midazolam, fentanyl combined with bupivacaine for obstetrics and gynecology after surgery is safe and effective,and the adverse reactions are mild,which is worthy of clinical application.
出处
《中国实用神经疾病杂志》
2012年第17期18-20,共3页
Chinese Journal of Practical Nervous Diseases
