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脑白质纤维解剖技术及扩散张量成像应用于视放射的观察与测量

Observation and Measurement of Optic Radiation Based on Diffusion Tensor Imaging and Cerebral White Matter Fiber Dissection Technique
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摘要 目的:采用脑白质纤维解剖技术及扩散张量成像(DTI)技术,对视放射的结构进行观察与测量,为眼科、神经外科疾病诊断及治疗提供科学依据。方法:15例成人大脑标本,用脑白质纤维剥离技术对视放射及其毗邻白质结构进行剥离、观察、测量及分析;DTI技术对10名健康志愿者行视放射纤维极其毗邻白质结构成像,并进行重建。结果:脑白质纤维剥离技术和DTI技术可清晰显示视放射的Meyer袢其毗邻白质纤维结构。Meyer袢距颞角前方、颞极后方、枕极分别为(4.44±0.55),(25.40±2.19),(105.1±4.10)mm,外矢状层距侧脑室外侧壁距离为(3.35±0.45)mm。DTI技术显示Meyer袢距颞角前方、颞极后方、枕极分别为(4.89±0.93),(26.67±2.27),(101.8±2.89)mm,外矢状层距侧脑室外侧壁距离为(3.38±0.47)mm;Meyer袢距颞角前方、颞极后方、枕极的距离,外矢状层距侧脑室外侧壁距离,分别用脑白质纤维剥离技术与DTI技术测量比较,差异无统计学意义(P=0.059,0.072,0.054,0.874)。结论:DTI技术可显示正常人的视放射纤维,与解剖学标本研究具有较好的一致性,可为颞叶手术术前计划的制定提供依据。 Objective: Technique to research optic radiation(OR) and the adjacent white matter structures using cerebral white matter fiber dissection technique and diffusion tensor imaging(DTI) for the diagnosis and treatment of ophthalmology diseases and neurosurgery diseases.Methods: Fifteen adult brain specimens were studied by cerebral white matter fiber dissection technique,special for optic radiation and adjacent to white matter structures;DTI technology was applied for imaging optic radiation fibers and adjacent to white matter structure in 10 healthy volunteers.Results: Meyer loop in the optic radiation and adjacent white matter fiber structures were clearly showed by cerebral white matter fiber dissection technique.The mean distances between the Meyer loop of OR and temporal thetemporal horn,temporal pole,ahead of the rear occipital pole were(4.44±0.55),(25.40±2.19),and(105.1±4.10) mm,respectively.The mean distances between the sagittal layer and the lateral wall of the lateral ventricle were(3.35±0.45) and(3.38±0.47) mm,respectively.No significant differences were found between brain white matter fiber dissection technique and DTI technique in these above measurements.Conclusion: There might be a consistence in the normal human optic radiation fibers detected by DTI and cerebral white matter fiber dissection technique,so this study provides a theoretic basis of DTI in the patients before performing operation in the temporal lobe.
出处 《武汉大学学报(医学版)》 CAS 北大核心 2012年第5期677-679,683,共4页 Medical Journal of Wuhan University
关键词 视放射 脑白质 扩散张量成像 观察 测量 Optic Radiation White Matter Diffusion Tensor Imaging Observation Measurement
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