摘要
目的:探讨榄香烯与卡介苗(BCG)在预防浅表性膀胱癌术后复发的疗效及毒副作用。方法:浅表性膀胱癌患者47例,随机分为榄香烯组23例和BCG组24例,TURBt术后1周作膀胱灌注,每周1次,共8周,随后每月1次,共12个月。观察两组疗效及副作用。结果:榄香烯组复发率为13.04%,BCG组复发率为12.5%,榄香烯组与BCG组之间复发率无显著性差异(P>0.05)。榄香烯组出现膀胱刺激者3例(13.04%),无严重血尿及尿道狭窄,BCG组膀胱刺激症8例(33.33%),出现血尿1例(4.16%),无尿道狭窄。两组不良反应相比有显著性差异(P<0.05)。结论:榄香烯能够较好预防浅表性膀胱癌复发,毒副作用较小。
Objective：To investigate the curative effect and side effect of elemene and BCG in preventing the recurrence of postoperative superficial bladder. Methods： The forty-seven superficial bladder patients were ran- domly assigned elemene group and BCG group after TURBt. The patients reperfused after one-week operation for 8 weeks, and then once time every-month in the last 12 months. Compared the therapeutic effect between the two groups. Results ： The recurrence rate of elemene group and BCG group were 13. 04% and 12. 5%, no obvious difference. They all hadn＇t urethral stricture. The bladder irritation rate of elemene group and BCG group were 13.04 % and 33.33 %, respectively. Conclusion：The elemene can prevent the recurrence of postoperative superficial bladder, and a few adverse reactions.
出处
《陕西医学杂志》
CAS
2012年第9期1151-1152,共2页
Shaanxi Medical Journal
关键词
膀胱肿瘤/预防和控制
抗肿瘤药/治疗应用
卡介苗/治疗应用
对比研究
Bladder neoplasms/prevention and control Antineoplasic agents/therapeutic use BCG vaccine/therapeutic use Comparative study
