摘要
目的评估上消化道腺瘤患者中结直肠肿瘤（腺瘤和癌）的患病情况。方法回顾性分析2007年至2011年消化内镜检查的患者，选取经病理证实为上消化道腺瘤并且行结肠镜检查的39例作为病例组，选取同期行胃肠镜检查而胃镜示无腺瘤并且性别年龄匹配的78例作为对照组，比较两组结直肠肿瘤患病情况的差异。结果病例组结直肠肿瘤的检出率为51．3％（20／39），其中腺瘤的检出率为38．5％（15／39），癌的检出率为12．8％（5／39）。对照组中结直肠肿瘤的检出率为14．1％（11／78），其中腺瘤的检出率为12．8％（10／78），癌的检出率为1．3％（1／78）。病例组结直肠肿瘤的检出率明显高于对照组（P〈0．001），其中结肠腺瘤和结肠癌的检出率也均分别高于对照组（50．0％比12．5％和52．2％比15．2％）。分别将胃、十二指肠腺瘤进行单独比较，亦发现两组结直肠肿瘤检出率均显著高于相应对照组。结论上消化道腺瘤的患者结直肠肿瘤的检出率较高，建议及时行结肠镜检查。
Objective To evaluate the risk of colorectal neoplasia among patients with gastric or duodenal adenoma. Methods We retrospectively reviewed 39 patients with gastric or duodenal adenomas between 2007 and 2011 as the study group. A total of 78 patients without upper gastrointestinal adenomas who underwent colonoseopy were included as a control group. Colonoscopie findings were compared between the two groups. Results Positive finding rate of colorectal neoplasia in study group was 51.3% （20/39） , with adenomas in 38.5% （15/39） and cancer in 12. 8% （5/39）, which were all significantly higher than those of the control group, 14. 1% （11/78） （ P 〈 0. 001 ）, 12. 8% （10/78） （P 〈 0. 05 ） and 1.3% （1/78） （P 〈 0. 05 ）, respectively. The results were similar when upper digestive tract was further divided into stomach and duodenum（50. 0% vs. 12. 5% and 52. 2% vs. 15.2% ）. Conclusion Patients with gastric or duodenal adenomas are at a significantly higher risk for colorectal neoplasia. Colonoscopy should be recommended for these patients.
出处
《中华消化内镜杂志》
2012年第9期500-502,共3页
Chinese Journal of Digestive Endoscopy
基金
基金项目：国家自然科学基金资助项目（81070283）
关键词
胃腺瘤
十二指肠腺瘤
结直肠肿瘤
结肠镜
Gastric adenomas
Duodenal adenomas
Colorectal neoplasia
Colonoscopy
