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盐酸氨溴索联合曲安奈德鼓室内注射治疗分泌性中耳炎的临床疗效研究 被引量:9

Clinical Effect of Ambroxolhydrochloride and Triamcinolone Acetonide Injected into Tympanum on Secretory Otitis Media
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摘要 目的探讨并分析鼓室内注入盐酸氨溴索及醋酸曲安奈德注射液治疗分泌性中耳炎的临床疗效。方法选取70例确诊为分泌性中耳炎的患者作为研究对象,随机分为治疗组和对照组,两组各35例。对照组给予口服克拉霉素分散片加泼尼松龙片;治疗组于鼓室内注射盐酸氨溴索及醋酸曲安奈德注射液进行治疗;对两组治疗前及治疗3个月后不同频率下气导平均听阈及咽鼓管恢复情况进行统计分析,并对两种患者总体疗效进行评价。结果治疗组和对照组总有效率分别为91.4%、62.9%,差异有统计学意义(P<0.05);两组治疗3个月后在0.5kHz、1.0kHz、2.0kHz频率下气导平均听阈及咽鼓管功能均有显著改善,且治疗组优于对照组,差异均有统计学意义(P<0.05)。结论与对照组相比,鼓室内注入盐酸氨溴索及醋酸曲安奈德注射液治疗分泌性中耳炎,具有疗效确切、操作简单的特点,值得临床推广应用。 Objective To observe the clinical effect of ambroxolhydrochloride and triamcinolone acetonide injected into tympanum on secretory otitis media.Methods 70 patients with secretory otitis media were divided randomly into treatment group(35 cases)and control group(35 cases).Injection of ambroxolhydrochloride and triamcinolone acetonide into tympanum were used in treatment group,while clarithromycin dispersible tablets and prednisolone tablets in control group.Therapeutic、puretone threshold average by air conduction and recovery of auditory tube of both groups were observed before the treatment and the follow-up of 3 months.Results The total effective rate of treatment group(91.4%)was significantly superior to that of control group(62.9%)(P〈0.05).The condition of puretone threshold average by air conduction at 0.5KHz、1.0KHz、2.0KHz and the function of auditory tube of both groups after treatment were significantly better than that of both groups before treatment,but improvement of treatment group was superior to that of control group(P〈0.05).Conclusion The clinical effect of ambroxolhydrochloride and triamcinolone acetonide injected into tympanum on secretory otitis media was superior to that of control group,it is a useful and simple formula for treating secretory otitis media and worth popularizing
作者 郝勇
出处 《中外医疗》 2012年第23期98-99,101,共3页 China & Foreign Medical Treatment
关键词 分泌性中耳炎 鼓室内注射 盐酸氨溴索 醋酸曲安奈德注射液 Secretory otitis media; Tympanum injection; Ambroxolhydrochloride; Triamcinolone acetonide
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