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检测抗CCP自身抗体在类风湿关节炎诊治中的作用 被引量：6

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摘要 类风湿关节炎(RA)是一种全身性的自身免疫病,以滑膜血管翳形成为特征,最终导致软骨破坏、骨侵蚀和关节残疾。早期诊断和治疗可以改善RA的结局。迄今,对RA诊断价值最高的生物学标志物是抗环瓜氨酸肽自身抗体(ACCP)。本文对ACCP的形成及其在RA发病中的作用进行简要综述。
作者 刘阳 李晓军
机构地区 南京军区南京总医院临床中心实验科
出处 《临床检验杂志》 CAS CSCD 北大核心 2012年第8期602-604,共3页 Chinese Journal of Clinical Laboratory Science
基金 江苏省科技支撑计划-社会发展项目(BE2011786) 国家自然科学基金(81071419)
关键词 类风湿关节炎 环瓜氨酸肽 自身抗体
分类号 R446.6 [医药卫生—诊断学]
  • 相关文献

参考文献30

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二级参考文献28

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共引文献17

同被引文献36

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引证文献6

二级引证文献24

临床检验杂志
2012年 第8期

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