摘要
目的加强对癫痫伴慢波睡眠期持续棘慢波(CSWS)临床、脑电图特征的认识,强调早期诊断及治疗的重要性。方法回顾性分析5例CSWS患者临床、脑电图特征及治疗情况,并对患者进行6个月～1.5 a随访。结果 5例患者,男3例、女2例,癫痫起病年龄1岁1个月～7岁8个月。2例存在脑部静止性病变,3例头影像学未见异常。4例患者以夜间发作首发,1例以清醒期全面强直阵挛发作起病,逐渐出现全面性脑功能减退,脑电图具备特征性慢波睡眠期持续性放电。4例在激素治疗3个月后临床症状及脑电图明显改善,1例激素治疗6个月后复发。结论 CSWS早期表现不典型,早期诊断及激素治疗可改善患者认知。
Objective To recognize the characteristics of chnic and electroencephalogram （EEG） of epilepsy with continuous spike-and-wave during slow wave sleep （ CSWS）, and to emphasize the importance of early diagnosis and treat ment. Method To review the characters of clinic and EEG of five patients with CSWS, and follow up for 6-18 months. Results In five patients with CSWS, 3 were male and 2 were female. The onset age of epilepsy was one year and one month to seven years and eight months years old. MRI of brain was abnormal in 2 of 5 patients. Four patients had their first seizure at night, one patient had tonic-clonic seizure at alarm state, then they had global cognitive declined. There was phenomenon of ESES in their EEG. Positive response to corticoid was found during the first 3 months of treatment in 4 of 5 patients. Relapse occurred in 1 of them after six months. Conclusion The clinic characters of CSWS may be not typical at early phase, early diagnosis and appropriate corticoid treatment can improve the cognition.
出处
《山东医药》
CAS
2012年第32期4-7,共4页
Shandong Medical Journal
关键词
癫痫伴慢波睡眠期持续棘慢波综合征
儿童
脑电图
临床
治疗
epilepsy with continuous spike-and-wave during slow wave sleep
children
electroencephalogram
clinic
treatment
