摘要
宫颈腺癌是宫颈癌的一种特殊病理类型,较鳞癌少见。近年来,宫颈腺癌的发病率及其在宫颈癌中所占比例不断上升,且发病趋于年轻化,预后比同期鳞癌差。此外,宫颈腺癌卵巢转移率高于鳞癌,对放、化疗的敏感性显著低于鳞癌,这些均对宫颈腺癌的诊治有重要影响。从宫颈腺癌致病因素(雌激素、孕激素与人乳头瘤病毒)、卵巢转移高危因素及卵巢保留以及放化疗进展3个热点问题着手,简述近年来宫颈腺癌的研究进展。
Cervical adenocarcinoma(CA),fewer than squamous cell carcinoma(SCC),is a special pathological type of cervical cancer.Recently,there is a rising incidence and proportion of CA related to cervical cancer.CA is more often seen in younger population and has a poorer prognosis than SCC.In addition,compared with SCC,higher rate of ovarian metastasis and lower sensitivity to both radiotherapy and chemotherapy affect the diagnosis and treatment of CA.The research progress of cervical adenocarcinoma was reviewed in this article,focused on the pathogenic factors(estrogen,progesterone and human papillomaviidae),risk factors for ovary metastasis,ovarian preservation and the clinical applications of radiotherapy and chemotherapy.
出处
《国际妇产科学杂志》
CAS
2012年第4期330-333,共4页
Journal of International Obstetrics and Gynecology
关键词
宫颈肿瘤
腺癌
乳头状瘤病毒科
雌激素类
孕激素类
放射疗法
药物疗法
Uterine cervical neoplasms
Adenocarcinoma
Papillomaviridae
Estrogens
Progestins
Radiotherapy
Drug therapy