摘要
目的探讨曲马多用于不停跳冠状动脉旁路移植术(OPCABG)后镇痛的有效性与安全性。方法 OPCABG患者64例,随机均分为两组,术中均吸入1%七氟醚和静注舒芬太尼维持麻醉,关闭胸骨前分别采用曲马多(T组)和舒芬太尼(S组)自控镇痛。记录患者疼痛VAS评分、镇静评分及不良反应。结果 T组静息VAS评分显著低于S组(P<0.05)。两组术后清醒时间和机械通气时间差异无统计学意义。结论曲马多用于OPCABG术后镇痛具有良好的镇痛效果。
Objective To investigate the efficacy and safety of tramadol for postoperative analgesia after off-pump coronary bypass graft surgery （OPCABG）. Methods Sixty-four patients undergoing OPCABG were randomly divided into two groups： tramadol group （group T） and sufentanil group （group S）. Before sterna closure, the patients in the groups T and S received Iramadol 1 mg/kg and sufentanil 0.1μg/kg, respectively. After the operation, the patient controlled analgesia devices with tramadol or sufentanil were connected. Visual analogue scale （VAS）, and sedation level were recored. Results The resting VAS score in group T was lower than in group S at 12 h, 24 h, 48 h after operation （P〈0. 05）. The moving VAS score was lower in group T than in group S at 24 h and 48 h （P〈0.05）. The sedation level was lower in group T than in group S at 24 h （P 〈 0.01）. Conclusion Tramadol produces more analgesic effects than sulfentanyl for postoperative pain relief in patients undergoing OPCABG.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2012年第8期778-780,共3页
Journal of Clinical Anesthesiology
