摘要
目的:探讨动脉导管未闭(PDA)患者介入封堵治疗后肺动脉压改变的影响因素。方法:回顾性分析2008年1月至2011年9月在我院行介入封堵治疗的43例PDA患者的临床及介入手术资料。结果:与治疗前比较,PDA患者介入封堵治疗后肺动脉收缩压[PASP,(76±51)mmHg比(46.26±17.26)mmHg]、肺动脉舒张压[PADP,(39.47±17.11)mmHg比(15.84±10.74)mmHg]、平均肺动脉压[MPAP,(54.72±19.21)mmHg比(28.53±14.41)mmHg]均显著降低(P均=0.0001),PADP下降程度比PASP更明显[(0.54±0.38)比(0.38±0.15),P=0.012];PDA患者介入治疗后PASP、MPAP下降程度与年龄呈负相关(B=-0.04,P=0.012;B=-0.006,P=0.009);术后MPAP下降程度与动脉导管管径呈正相关(B=0.022,P=0.01)。结论:介入封堵治疗对动脉导管未闭有益,应在年龄较小时尽早手术。
Objective：To analyze influencing factors of change of pulmonary artery pressure after interventional transcatheter closure in patients with patent ductus arteriosus（PDA）.Methods： Clinical and intervention data of 43 PDA patients undergoing interventional transcatheter closure in our hospital from Jan 2008 to Sep 2011 were retrospectively analyzed.Results：Compared with before treatment,there were significant decrease in pulmonary arterial systolic pressure,pulmonary arterial diastolic pressure and mean pulmonary arterial pressure in PDA patients after interventional transcatheter closure（P=0.0001 all）,decrease degree of PADP was more significant than that of PASP [（0.54±0.38）vs.（0.38±0.15）,P=0.012];decrease degree of PASP and MPAP in PDA patients after interventional transcatheter closure were negatively correlated with age（B=-0.04,P=0.012;B=-0.006,P=0.009）;decrease degree of MPAP after operation was positively correlated with ductus arteriosus diameter（B=0.022,P=0.01）.Conclusion： Interventional transcatheter closure is beneficial for patients with patent ductus arteriosus and patients should receive operation as young as possible.
出处
《心血管康复医学杂志》
CAS
2012年第4期409-412,共4页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
动脉导管未闭
导管插入术
肺动脉
血压
Ductus arteriosus
patent
Catheterization
Pulmonary artery
Blood pressure
