摘要
植物微丝参与了许多重要的细胞生理活动,与植物耐盐性有密切的联系。在微丝解聚剂Latrunculin B(LatB)存在的情况下,拟南芥会表现出盐胁迫敏感。本研究结果表明盐胁迫下LatB可增加拟南芥线粒体膜通透性转换孔(mitochondrial permeability transition pore,MPTP)开放度,导致线粒体膜电势下降和细胞色素C的释放。而加入MPTP抑制剂环孢素A(CsA)后,膜电势下降程度降低,细胞色素C释放减少,解聚微丝造成的盐敏感表型得到一定程度恢复。
The microfilaments （MFs） in plants involved in many important cellular physiological activities and were closely linked to plant salt tolerance. In the presence of the MF depolymerization drugs （Latrunculin B, LatB）, the Arabidopsis seedlings displayed salt sensitivity. The experimental results showed that LatB could promote the opening of the mitochondrial permeability transition pore （MPTP） under salt stress, which further led to decrease of mitochondrial membrane potential and release of cytochrome C. On the other hand, cyclosporine A （CsA）, the MPTP inhibitor, could reduce the decrease of mitochondrial membrane potential and release of cytochrome C, and partially recover the salt-sensitive phenotype caused by LatB.
出处
《植物生理学报》
CAS
CSCD
北大核心
2012年第8期759-766,共8页
Plant Physiology Journal
基金
北京林业大学新进教师科研启动基金项目(2010BLX03)
关键词
盐胁迫
线粒体
细胞骨架
微丝解聚
salt stress
mitochondrion
cytoskeleton
microfilaments depolymerization
