摘要
目的探讨胰十二指肠切除术术后胰瘘发生的高危因素。方法回顾性分析4年间在南京军区福州总院肝胆外科行胰十二指肠切除术的87例患者的临床资料,分析可能与胰瘘有关的8个因素,进行单因素及逐步Logistic多因素分析。结果术后并发症发生率为35.6%(31/87),其中胰瘘10例,发生率为11.5%,占总并发症的32.3%。多因素Logistic回归分析表明术前总胆红素水平(TBil≥171μmol/L)、胰腺质地软为胰瘘发生的独立危险因素。结论术前TBil水平(TBil≥171μmol/L)和胰腺质地软预示着较高的胰瘘发生率。
Objective To investigate the risk factors of developing pancreatic fistula after pancreaticoduodenectomy. Methods Eighty - five patients who underwent pancreaticoduodenectomy in the Department of Hepatobiliary Surgery of Fuzhou General Hospital between Janu- ary 2008 and February 2012 were studied. The management strategy and outcome, including pancreatic fistula, were evaluated. Eight poten- tial risk factors for formation of pancreatic fistula were analyzed with univariate and multivariate logistic regression models. Results Pancre- atic fistula occurred in ten of the patients, and accounted for 32. 3% of the overall morbidity. Multivariate logistic regression analysis re- vealed that a preoperative total bilirubin （TBil） level of ≥171 μmol/L and soft texture of the pancreas were independent risk factors for pancreatic fistula. Conclusion Preoperative TBil≥171μmol/L and soft texture of the pancreas predict a high probability of pancreatic fistula formation after pancreaticoduodenectomy.
出处
《临床肝胆病杂志》
CAS
2012年第8期587-588,602,共3页
Journal of Clinical Hepatology
关键词
胰十二指肠切除术
胰腺瘘
危险因素
pancreaticoduodenectomy
pancreatic fistula
risk factors
