摘要
环氧化物水解酶是一种能水解环氧化合物的酶,它能够立体选择性水解外消旋的环氧化物产生手性环氧化物和手性二醇。它普遍存在于动植物、昆虫及微生物体内,应用其合成手性的环氧化合物及其产物手性醇,受到了科学工作者们的广泛关注。本文综述了环氧化物水解酶的对映会聚水解及其在制备手性环氧化物和手性邻二醇中的应用。
The epoxide hydrolase is an enzyme in the hydrolysis of epoxides, and it can stereoselective hydrolysis the racemic epoxide to chiral epoxides and chiral diol. It is commonly found in plants, animals, insects and mi-croorganisms. It was applicated to synthesis the chiral epoxides and their products of chiral alcohols, which had been widespread concern of scientists. In this paper, the bioconvergence hydrolysis of epoxide hydrolase applied to prepare chiral epoxides and chiral idols had been reviewed.
出处
《食品与发酵科技》
CAS
2012年第4期67-70,74,共5页
Food and Fermentation Science & Technology
基金
浙江省自然科学基金项目(No.Y2080303
Z4080032)
