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ST2与心肌梗死和心力衰竭的关系 被引量:15

Relationship between ST2 and myocardial infarction or heart failure
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摘要 白介素1(interleukin-1,IL-1)受体家族包括IL-1R、IL-18R及其辅助蛋白IL-1RAcP、IL-18RAcP等。1989年,ST2作为IL-1受体家族的新成员被发现,之后证实其参与多种病理生理过程,在炎症和变态反应性疾病中发挥重要作用,但因当时未发现其功能性配体,故长期以来ST2一直被认为是一个孤儿受体。直到2005年,IL-33作为ST2的特异性功能配体被发现,于是针对ST2的研究又有了新的进展。
作者 张堃 张新超
出处 《中国心血管杂志》 2012年第4期314-316,共3页 Chinese Journal of Cardiovascular Medicine
关键词 ST2 白介素-33 心肌梗死 心力衰竭 心肌重构 ST2 IL-33 Myocardial infarction Heart failure Cardiac remodeling
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参考文献21

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