摘要
目的探讨影响青年早期宫颈癌的预后及影响因素。方法回顾性分析了105例35岁以下早期宫颈癌患者预后及影响因素,Ⅰa期18例(17.14%),1b期23例(21.90%),Ⅱa期64例(60.95%)。结果 2年生存率为80.03%,5年生存率为73.18%。单因素分析显示预后与临床分期、病理分级、肿瘤大小、深肌层、脉管是否有癌细胞浸润、盆腔淋巴结是否转移、多个性伴侣+合并妊娠、孕次和产次、治疗方式有密切关系(P<0.05),与民族、病理类型、肿瘤类型、初产年龄无关(P>0.05);多因素分析显示临床分期、癌细胞分化程度、盆腔淋巴结转移、治疗方式是影响宫颈癌预后的主要危险因素(P<0.05)。结论具有高危因素的宫颈癌患者预后较差,应予高度重视并早发现早治疗,加强术后辅助治疗。
Objective To evaluate prognostic factors in patients with stage I a- II a of young cervical carcinoma. Methods 105 young group cases of cervical cancer were retrospectively analysed, including FIGO stage I a, 18 cases （17.14%）; I b 23 cases （21.90%） and II a 64 cases（60.95%）.Flesults The 2- year and 5- year survival rates were 80.03%, 73.18% respectively. In univariate survival analysis, clinical stage, differentiation of the carcinoma cells, tumor size ,deep stroma invasion, vessel tumor embolus, the metastasis of pelvic lymph nodes, gravidity and parity 〉3, multiple sexual partners during pregnancy and treatment approach were relevant to the prognosis of cervical cancer（P〈0.05）. Furthermore, the higher risk prognostic factors in COX regressive analysis were the later clinical stage, the lower grade of differentiation, the metastasis of pelvic lymph nodes and treatment approach （P〈0.05）. Conclusion The prognosis of cervical cancer patients with high risk factors could be poor, who should be strictly performed early diagnose and treat, postoperative adjuvant therapy should be considered for early stage cervical cancer
出处
《当代医学》
2012年第24期33-35,共3页
Contemporary Medicine
关键词
宫颈癌
青年
早期
生存分析
Cervical cancer
Young
Early stage
Survival analysis
