摘要
目的探讨64层螺旋CT对急性冠脉综合征患者斑块成分的诊断价值,并与血管内超声对比,评价其可靠性。方法经临床诊断为急性冠脉综合征患者15名,血管内超声检查发现冠状动脉斑块的12名患者进64层螺旋CT冠状动脉动脉成像检查,获取相关数据,应用64层螺旋CT工作站相关的后处理技术对动脉粥样斑块进行分析,并与血管内超声检查结果进行对比分析。结果 12名患者132个冠状动脉段纳入分析,CTA50个血管段正常,82个有斑块;血管内超声64个节段正常,68个有斑块。CTA对冠状动脉动脉斑块探测的敏感性为100%(68/68),特异性为82.9%(68/82);在区别钙化和非钙化斑块方面,CTA敏感性为100%(52/52),特异性为89.7%(52/58)。结论 CTA能对冠状动脉斑块的形态学特征作出精确评价,可作为一种有效的无创性手段对急性冠脉事件的发生做出预防及易损性斑块的治疗作出指导。
Objective To evaluate the ability of 64-slice CT angiography （CTA） assessing the vulnerable of coronary artery atherosclerotic plaques. Methods atients undergoing ul- tra-vascular ultrasound for clinical indications underwent 64-slice CT angiography liar the evaluation of plaque morphology. CT angiography data were evaluated for the presence anmorphology of plaque in the coronary artery segments. The results were blindly com- pared with intra-vascular ultrasound results on a segment by segment. Results Coronary artery segments were analyzed. Segments were norma and contained plaque. To determine coronary artery segments with any plaque, CT angiography had a sensitivity 100 % （68of 68） and specificity of 82.9% （68 of 82） To determine plaque morphology as calcified （fibrocalcific and calcific versus noncalcified （soft and fibrous）, CT angiography had a sensitivity of 100% （52 of 52） and a specificity of 89.7% （52of 58）. Conclusion CT angiography can accurately characterize plaque morphology and can be a useful tool in noninvasive evaluation of vulnerable plaque.
出处
《中国CT和MRI杂志》
2012年第4期33-36,共4页
Chinese Journal of CT and MRI
基金
深圳市科技计划项目(编号:201003223)
