摘要
目的研究阿卡波糖联合二甲双胍治疗2型糖尿病的临床疗效及安全性。方法选择2006年1月至2010年12月医院收治的2型糖尿病患者100例,随机分成两组,每组各50例。对照组给予二甲双胍治疗,治疗组给予阿卡波糖联合二甲双胍治疗,两组疗程均为12周。治疗12周后,复查患者空腹血糖、餐后2 h血糖,比较两组临床疗效。结果治疗后两组患者血糖比较,差异有统计学意义(P<0.05);对照组总有效率为82.00%,治疗组总有效率为96.00%,治疗组明显优于对照组(P<0.05)。两组均未出现严重不良反应,差异无统计学意义(P>0.05)。结论阿卡波糖联合二甲双胍治疗2型糖尿病安全、有效,值得在临床上推广使用。
Objective To study the clinical efficacy and safety of acarbose combined with metformin in the treatment of type 2 diabetes mellitus（T2DM）.Methods A hundred patients with T2DM treated in our hospital from January 2006 to December 2010 were selected and randomly divided into two groups,50 cases in each group.The control group was given metformin,while the treatment group received acarbose combined with metformin.The treatment course lasted for 12 weeks in the two groups.After 12 weeks of treatment,the fasting blood glucose and 2 h postprandial blood glucose were redetected and the clinical efficacy was compared between the two groups.Results The total effective rate was 82.00%in the control group and was 96.00% in the treatment group,showing statistical difference between them（P0.05）.Two groups showed no statistical difference in adverse reactions（P0.05）.Conclusion Acarbose combined metformin in the treatment of T2DM is safe and effective,which is worthy of being generalized in clinical practice.
出处
《中国药业》
CAS
2012年第15期97-98,共2页
China Pharmaceuticals
关键词
阿卡波糖
二甲双胍
2型糖尿病
疗效
acarbose
metformin
type 2 diabetes mellitus
efficacy
