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白癜风患者的血小板表面相关抗体

The surface associated antibodies of platelets of patients with vitiligo
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摘要 目的 为了进一步探讨白癜风患者免疫功能及血小板低下的原因。方法 对 3 0例仅伴血小板减少的白癜风患者作了血小板表面相关抗体测定 [PAIgG、PAIgA、PAIgM],并观察其治疗前后的变化。 结果 本组血小板表面相关抗体PAIgG、PAIgA、PAIgM的均值显著高于正常对照组 ,经治疗后PAIgG的值也随病情好转而下降。结论 本文表明白癜风患者的血小板减少属免疫源性。 Objective To appraise the cause of reduced immune function and platelet count in patients with vitiligo. Methods The surface associated antibodies (PAIgG,PAIgA, PAIgM) of platelets were determined in 30 patients with vitiligo whose platelet counts were reduced and changes were observed before and after the treatment. Results The mean values of PAIgG, PAIgA, PAIgM were found to be elevated and were significantly higher than those of normal controls, but the PAIgG declined with clinical improvement synchronously.Conclusion It is suggested that the thrombocytopenia of vitiligo is primarily immunogenic.(Shanghai Med J, 2000,23∶142 144)
出处 《上海医学》 CAS CSCD 北大核心 2000年第3期142-144,共3页 Shanghai Medical Journal
关键词 白癜风 血小板 表面相关抗体 血小板减少 Vitiligo Ssurface associated antibodies Platelet
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