摘要
目的探讨超声引导下经会阴部前列腺穿刺活组织检查术在前列腺癌诊断中的作用和意义,以及影响前列腺癌诊断的各种相关因素。方法回顾性总结268例在超声引导下经会阴部前列腺穿刺活组织检查患者的超声显像结果及病理资料,并对影响前列腺癌诊断的各种相关因素进行分析。结果 268例患者的前列腺癌检出率为38.1%(102/268)。将患者分为≤60岁组(41例)、>60岁且≤70岁组(76例)、>70岁且≤80岁组(107例)及>80岁组(44例),4组的前列腺癌检出率分别为17.1%(7/41)、26.3%(20/76)、50.5%(54/107)及47.7%(21/44),各组间差异均有统计学意义(P值均<0.01)。230例检测前列腺特异性抗原(PSA)水平患者的前列腺癌检出率为32.6%(75/230)。根据PSA水平将患者分为PSA≤4ng/mL组(13例)、>4ng/mL且≤10ng/mL组(122例)、>10ng/mL且≤20ng/mL组(56例)、>20ng/mL且≤30ng/mL组(10例)及>30ng/mL组(29例),5组的前列腺癌检出率分别为0、24.6%(30/122)、30.4%(17/56)、40.0%(4/10)、82.8%(24/29),各组间差异均有统计学意义(P值均<0.01)。232例通过经直肠超声检查或磁共振成像测量前列腺体积患者的前列腺癌检出率为37.5%(87/232)。根据前列腺体积将患者分为前列腺体积≤50mL组(155例)及>50mL组(77例),两组的前列腺癌检出率分别为45.8%(71/155)及20.8%(16/77),两组间差异有统计学意义(P<0.01)。结论超声引导下经会阴部前列腺穿刺活组织检查在前列腺癌的诊断中具有重要意义。
Objective To evaluate the value of transperineal ultrasound-guided prostate biopsy in the diagnosis of prostate cancer and analyze the prostate-cancer-related factors. Methods Transperineal ultrasound-guided prostate biopsy was performed in 268 subjects in this study. The pathologic results and ultrasonic data were compared and the prostate-cancer-related factors were retrospectively analyzed. Results The detection rate of prostate cancer was 38.1% （102/268）. Patients were divided into 4 groups according to age： ≤60 years group （n=41）, 60 and ≤70 years group （n=76）,70 and ≤80 years group （n=107） group, and 80 years group （n=44）. The detection rates of prostate cancer in the 4 groups were 17.1% （7/41）, 26.3% （20/76）, 50.5% （54/107） and 47.7% （21/44）, respectively. There were statistical differences among different groups （all P0.01）. Prostatespecific antigen （PSA） levels were tested in 230 patients, and the prostate cancer detection rate was 32.6% （75/230）. Then the 230 patients were divided into 5 groups according to PSA levels： PSA ≤4 ng/mL group （n=13）, 4 and ≤10 ng/mL group （n=122）, 10 and ≤20 ng/mL group （n=56）, 20 and ≤30 ng/mL group （n=10）, and 30 ng/mL group （n=29）. The detection rates of prostate cancer in the 5 groups were 0, 24.6% （30/122）, 30.4% （17/56）, 40.0% （4/10） and 82.8% （24/29）, respectively. There were statistical differences among different groups （all P0.01）. Prostate volume was measured by transrectal ultrasonography （TRUS） or magnatic resonance imaging （MRI） in 232 patients, and the prostate cancer detection rate was 37.5% （87/232）. Patients were divided into two groups according to prostate volume： ≤50 mL group （n=155） and 50 mL group （n=77）, and the prostate cancer detection rate were 45.8% （71/155） and 20.8% （16/77）, respectively. There was statistical difference between the two groups （P 0.01）. Conclusion Transperineal ultrasound-guided prostate b
出处
《上海医学》
CAS
CSCD
北大核心
2012年第5期400-402,共3页
Shanghai Medical Journal
