摘要
药物洗脱支架大幅度减少了支架内再狭窄的发生率,然而随着药物洗脱支架的广泛应用,再狭窄患者的绝对数量是一个不容忽视的庞大数字。再狭窄的临床表现常常是再发心绞痛,但是有些患者表现为急性心肌梗死。再狭窄的发生可能和生物因素、机械因素、技术因素有关。再狭窄的类型主要是局限性的。
The drug-eluting stent ( DES ) has proved to be an important step toward reducing rates of restenosis and target lesion revas- cularization after percutaneous coronary intervention. However, the widespread use of DES and its incorporation into daily practice has led to significant numbers of patients presenting with DES failure. The clinical presentation of DES in-stent restenosis ( ISR } is usually recurrent angina, but some patients present with acute coronary syndrome. Mechanisms of DES ISR can be biological, mechanical, and technological.
出处
《心血管病学进展》
CAS
2012年第4期474-477,共4页
Advances in Cardiovascular Diseases
关键词
药物洗脱支架
支架内再狭窄
机制
治疗策略
drug-eluting stent
in-stent restenosis
mechanism
treatment strategies