摘要
目的了解和掌握1992-2009年天津市15岁以下儿童乙型肝炎疫苗免疫效果的变化趋势,为防治乙型肝炎提供科学依据。方法利用传染病疫情信息报告数据和1992、2005、2009年3次血清流行病学调查资料,采用统计软件分析免疫效果变化趋势。结果 1992-2009年期间,天津市15岁以下儿童乙型肝炎报告发病率呈逐年下降趋势,由7.06/10万下降到1.35/10万,下降了80.88%;HBsAg携带率呈逐年下降趋势,由4.02%下降到0.59%,下降了85.32%;HBsAb阳性率呈逐年上升趋势,由38.84%上升到64.94%,上升了67.20%;HBcAb阳性率呈逐年下降趋势,由27.23%下降到1.18%,下降了95.67%;疫苗接种率呈逐渐上升趋势,由34.82%上升到98.79%,上升了183.72%。结论天津市15岁以下儿童的乙型肝炎控制效果显著,主要与此人群疫苗接种率上升密切相关。
Objective To analyze the effect trend of Hepatitis B vaccine among group below 15 years old from 1992-2009,so as to provide scientific evidence for hepatitis B preventive measures.MethodsThe data about the incidence and the seroepidemiological surveys of hepatitis B among group below 15 years old from 1992-2009 were collected and analyzed by epidemiological description with statistical software.ResultsThe incidence of hepatitis B among group aged below 15 years was decreased by 80.88% from 7.06/100 000 in 1992 to 1.35/100 000 in 2009;The positive rate of HBsAg was decreased by 85.32% from 4.02% in 1992 to 0.59% in 2009;The positive rate of anti-HBs was increased by 67.20% from 38.84% in 1992 to 64.94% in 2009;The positive rate of HBcAg was decreased by 95.67% from 27.23% in 1992 to 1.18% in 2009;The rate of vaccination was increased by 183.72% from 34.82% in 1992 to 98.79% in 2009.ConclusionsThe control effect of hepatitis B in Tianjin,which is mainly related to the increased rate of vaccination,has achieved significant results.
出处
《中国预防医学杂志》
CAS
2012年第1期47-50,共4页
Chinese Preventive Medicine
