摘要
背景:目前临床上有关颈前路椎间盘切除减压植骨融合及人工椎间盘置换治疗颈椎病的效果尚未得出一致的结论。目的:对比颈前路融合与人工椎间盘置换治疗颈椎病的效果。方法:回顾性分析郑州大学第一附属医院骨科收治的颈椎病患者106例,其中19例行Bryan人工椎间盘置换(置换组),87例行单节段颈前路椎间盘切除减压植骨融合(融合组)。结果与结论:所有患者均获得随访,随访时间36～48个月。①两组患者随访时神经功能均得到明显恢复,末次随访时两组目测类比疼痛评分、JOA评分差异无显著性意义(P>0.05)。②融合组患者治疗后6个月植骨全部骨性融合,内固定无松动、脱落、断裂发生。置换组患者置换后无假体移位、脱落等并发症发生。③置换组置换后颈椎活动范围和置换节段活动范围与置换前相比差异无显著性意义(P>0.05)。全部患者均无严重并发症发生。提示单节段人工椎间盘置换后早期并发症少,Bryan人工颈椎间盘置换治疗颈椎病在取得满意临床疗效的同时能保留置换节段和颈椎的活动范围。
BACKGROUND： To data, there is no consistent conclusion on the effect of anterior cervical discectomy and fusion （ACDF） and artificial disc replacement in the treatment of cervical spondylosis. OBJECTIVE： To compare the effect of anterior cervical discectomy and artificial disc replacement in the treatment of cervical spondylosis. METHODS： 106 patients with cervical spondylosis were selected from Department of Orthopedics, the First Affiliated Hospital of Zhengzhou University to perform the retrospective analysis. Nineteen patients received Bryan artificial disc replacement （replacement group）, 87 patients received single-level ACDF （ACDF group）. RESULTS AND CONCLUSION： All the patients were followed-up for 36-48 months. ~The neurological function of two groups was significantly restored during follow-up, and there was no significant difference of visual analogue scores and JOA scores between two groups during final follow-up （P 〉 0.05）. GAll patients of the ACDF group achieved bone fusion at 6 months after operation without internal fixation loosening, dislocation or breakage. No complications such as prosthesis migration or loosening occurred in replacement group. As for the range of motion of cervical vertebrae and the replacement segment of cervical vertebrae, there was no statistical difference before and after operation （P 〉 0.05）. No serious complications occurred. Single-level artificial disc replacement has fewer complications in the early stage, and the Bryan artificial disc replacement can achieve the satisfactory clinical outcome and preserve the range of motion of cervical vertebrae and the replacement segment of cervical vertebrae.
出处
《中国组织工程研究》
CAS
CSCD
2012年第30期5529-5533,共5页
Chinese Journal of Tissue Engineering Research
