摘要
目的探讨参芪转律胶囊配合西药常规治疗冠心病收缩性心力衰竭合并室性早搏的临床疗效。方法将我院自2009-04～2011-04收治的86例患者按照对照、双盲的原则随机分为观察组(参芪转律胶囊合并西药常规治疗组)和对照组(常规治疗组),每组各43例。两组均采用扩张冠脉、抗血小板聚集、降压利尿、及血管紧张素转化酶抑制剂等西医常规治疗方法,观察组在常规治疗的基础上加服参芪转律胶囊,对照组加服美托洛尔抗心律失常药治疗。持续治疗4周,观察心功能是否有所改善。结果对于心功能改善情况,观察组总有效率74.4%,共32例患者;对照组总有效率65.1%,共28例;室早有效率:观察组共38例,88.3%,对照组共27例,62.8%;不良反应发生率:观察组2.32%,仅1例,对照组20.9%,共9例。两组数据存在显著性差异(P<0.05),具有统计学意义。说明观察组的治疗效果更为显著。结论参芪转律胶囊配合西药常规治疗冠心病收缩性心力衰竭合并室性早搏临床效果显著,对患者心功能有良好的改善功能,可抗心律失常。
Objective To discuss the clinical efficacy of Shenqi Zhuanlv Capsule combined with conventional western medicine treatment on systolic heart failure of coronary heart disease companied by ventricular premature beats. Methods 86 patients admitted and treated in our hospital from April 2009 to April 2011 were randomized into the observation group （the group treated by Shenqi Zhuanlv Capsule combined with conventional western medicine treatment） and the control group （the group treated by conventional treatment ）. Each group included 43 patients. The two groups were both treated by conventional western medicine treatment, such as coronary artery dilatation, anti platelet aggregation, blood pressure lowering and diuresis, angiotensin converting enzyme inhibitor and the like. The observation group was also given Shenqi Zhuanlv Capsule and the control group was also given Metoprolol. After 4 weeks of continuous treatment, the heart function was observed. Results The overall response rate in heart function improvement of the observation group was 74. 4% （32 patients） and that of the control group was 65.1% （28 patients）. The response rate in ventricular premature beats of the observation group was 88.3% （38 patients） and that of the control group was 62.8% （27 patients）. The incidence rate of adverse reaction was 2. 32% （only 1 patient） and that of the control group was 20. 9% （9 patients）. The difference between the two groups was obvious （ P 〈 0. 05 ）, with statistical significance. It indicated that the treatment effect of the observation group was more significant. Conclusion The clinical efficacy of Shenqi Zhuanlv Capsule combined with conventional western treatment on systolic heart failure of coronary heart disease companied by ventricular premature beats is significant, can better improve heart function of patients and has antiarrhythmic effect.
出处
《延安大学学报（医学科学版）》
2012年第2期22-23,33,共3页
Journal of Yan'an University:Medical Science Edition
关键词
参芪转律胶囊
收缩性心率衰竭
室性早搏
抗心律失常
Shenqi Zhuanlv Capsule
systolic heart failure
ventricular premature beats
antiarrhythmia
