摘要
目的观察术前肌内注射曲马多对防治患者功能性鼻内窥镜术后躁动的临床效果。方法 100例在全麻下行功能性鼻内窥镜术患者随机分为曲马多组(A组)和对照组(B组),每组各50例。A组术前肌内注射曲马多2 mg/kg、长托宁1.0 mg,静脉诱导气管插管,维持以静吸复合麻醉。B组仅肌内注射长托宁1.0 mg,麻醉诱导维持同A组。观察两组患者术后呼吸恢复时间、苏醒时间、拔管时间、镇静情况、拔管前后心率、血压、躁动发生率及不良反应。结果 B组拔管时血压、心率明显高于A组(P<0.05),A组各时间点的血压、心率平稳;两组苏醒、拔管时间比较,差异无统计学意义,A组拔管时躁动发生率低于B组(P<0.05)。结论术前肌内注射曲马多能较好地预防、减轻功能性鼻内窥镜术患者术后躁动。
Objective To observe clinical effects of preoperative intramuscular injection of tramadol in preventing and treating emergence delirium after functional endoscopic sinus surgery （FESS）. Methods 100 cases of FESS under general anes- thesia were randomly divided into two groups, the tramadol group （A, n=50） and the control group （B, n=50）. The group A was in- tramuscularly injected with tramadol 2 mg/kg and penehyclidine hydrochloride 1.0 mg,performed intravenous induction and tra- cheal intubation, and then maintained with combined intravenous inhalational anesthesia. The group B was only intramuscularly administered with penehyclidine hydrochloride 1.0 mg,while intravenous induction and anesthesia maintainmeant were the same as the group A. The postoperative respiration recovery time, awakening time, extubation time, sedation scores, BP and HR before and after extubation,incidence rate of emergence delirium and adverse reactions were observed and recorded in the two groups. Results BP and HR during extubation in the group B were markedly higher than those in the group A （P〈0.05）. BP and HR at various time points in the group A exhibited steady. The awakening time and extubation time had no statistical difference between the two groups. Moreover, the incidence rate of emergence delirium in the group A was lower than that in the group B （P〈0.05）. Conclusion Preoperative intramuscular injection of tramadol can better prevent and reduce the emergency delirium after func- tional endoscopic sinus surgery.
出处
《现代医药卫生》
2012年第13期1942-1943,共2页
Journal of Modern Medicine & Health
