期刊文献+

周剂量多西他赛同步三维适形放疗治疗局部晚期非小细胞肺癌的临床分析 被引量:3

下载PDF
导出
摘要 目的观察周剂量多西他赛同步三维适形放疗治疗局部晚期非小细胞肺癌(NSCLC)的近期疗效及毒副反应。方法对50例局部晚期NSCLC患者,实施三维适形放射治疗方法,照射剂量60~70Gy,同步行多西他赛单药化疗,每周1次多西他赛25mg/m2,第1、8、15、22、28天各1次,共进行4—5次。结果50例患者全部完成治疗计划,完全缓解12.0%(6/50),部分缓解64.0%(32/50),有效率76.0%(38/50),无效和进展均为12.0%(6/50),放射性肺炎和放射性食管炎发生率为22%(11/50),白细胞下降发生率为64%(32/50)。结论周剂量多西他赛同步三维适形放疗治疗局部晚期NSCLC近期疗效较好,不良反应能为大多患者耐受。
出处 《中国医药》 2012年第8期950-951,共2页 China Medicine
  • 相关文献

参考文献14

二级参考文献43

共引文献116

同被引文献22

  • 1向作林,吴铮,李文如,曾昭冲,陈刚,白春学.紫杉醇化疗联合同步三维适形放疗治疗局部晚期非小细胞肺癌[J].中国临床医学,2005,12(2):318-320. 被引量:19
  • 2Hallqvist A,Wagenius G,Rylander H,et al.Concurrent cetux-imab and radiotherapy after docetaxel-cisplatin induction chemo-therapy in stage III NSCLC:satellite--a phase II study from theswedish lung cancer study group[J].Lung Cancer,2011,71:166-172. 被引量:1
  • 3Fischer JR,Griesinger F,Fink T,et al.Docetaxel-carboplatinchemotherapy combined with cetuximab in patients with locallyadvanced or metastatic non small-cell lung cancer(NSCLC)--re-sults of the nonrandomised phase II study TaxErb[J].LungCancer,2012,75:348-352. 被引量:1
  • 4Rosetti M,Zoli W,Tesei A,et al.Iressa strengthens the cyto-toxic effect of docetaxel in NSCLC models that harbor specificmolecular characteristics[J].Journal of cellular physiology,2007,212:710-716. 被引量:1
  • 5Weiss GJ,Vokes EE,Bunn PA,et al.Docetaxel and exisulindin previously treated non-small cell lung cancer(NSCLC)pa-tients:a multicenter,phase II clinical trial[J].J Thorac On-col,2007,2:933-938. 被引量:1
  • 6Nichols RC,Huh SN,Henderson RH,et al.Proton radiation therapy offers reduced normal lung and bone marrow exposure for patients receiving dose-escalated radiation therapy for unresectable stage Ⅲ non-small-cell lung cancer:A dosimetric study[J].Clinical Lung Cancer,2011,12(4):252-257. 被引量:1
  • 7Schubert LK,Gondi V,Sengbusch E,et al.Dosimetric comparison of left-sided whole breast irradiation with 3DCRT,forward-planned IMRT,inverse-planned IMRT,helical tomotherapy,and topotherapy[J].Radiotherapy and Oncology,2011,100(2):241-246. 被引量:1
  • 8Mislmani M,Grills IS,Robertson JM,et al.Stereotactic lung radiotherapy(SBRT)associated with improved local control compared to 3-dimensional conformal radiotherapy(3DCRT)for stage I non-small cell lung cancer(NSCLC)[J].International Journal of Radiation Oncology Biology Physics,2010,78(3):S512-S513. 被引量:1
  • 9柏茂树,伍治平,王熙才.肿瘤化疗辅助中药研究进展[J].现代肿瘤医学,2010,18(3):597-601. 被引量:48
  • 10黄德波,朱兆峰.周剂量多西他赛同步三维适形放疗治疗Ⅲ期非小细胞肺癌临床观察[J].肿瘤预防与治疗,2011,24(2):92-95. 被引量:1

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部