摘要
目的 为了提高重度急性有机磷农药中毒的抢救成功率 ,探讨换血治疗重度急性有机磷农药中毒的疗效。方法 对 3 6 0例重度急性有机磷农药中毒患者 ,随机分为换血组 (Ⅰ )和对照组 (Ⅱ )进行疗效对比。两组均接受阿托品及胆碱酯酶复能剂 (解磷定 )等综合治疗。Ⅰ组加用了换血治疗。结果 ( 1)胆碱酯酶 (CHE)活力恢复正常所需时间 ,Ⅰ组平均 5 6d ,Ⅱ组平均 11d ;( 2 )阿托品平均总用量Ⅰ组 ( 5 5 7 2± 12 6 7)mg ,Ⅱ组 ( 15 10 2± 78 83 )mg ,Ⅰ组比Ⅱ组明显减少。 ( 3 )两组治疗效果比较Ⅰ组明显优于Ⅱ组。经统计学处理所有指标均差异显著。结论 重度急性有机磷农药中毒的治疗 ,换血组比对照组疗效更好。
Objective To research the effect of curing serious acute organophosphorus pesticides poisoning by changing blood and improve the successful rate of first aid. Methods We divide 360 sufferers of serious acute organophosphorus pesticides poisoning into two groups to compare the curative effects,groupone (Ⅰ)is to change blood,group two (Ⅱ) is to contrast.Both of the two groups receive multiple treatments such as atropine pyridine aldoxinemethyliodide (PAM)and so on.In addition,group Ⅰ is given the treatment of changing blood. Results (1) It takes 5,6 days for cholinesterase (CHE) vitality to renew as ucual in group Ⅰ,while 11 days in group Ⅱ(P<0.01),(2) The dosage of atropine in group Ⅰ( 557.2±12.67)mg is greatly less than in group Ⅱ(1510.2±78.83)mg,P<0.01;(3)The curative effects including curing rate,death rate and so on of group Ⅰ are obviously better than those of group Ⅱ. After the process of statistics,all the indexes have conspicuous difference. Conclusion The resulf indicated that changing blood is a better treatment than contrasing group for serious acute organophosphorus pesticides poisoning.
出处
《河北医药》
CAS
2000年第1期31-33,共3页
Hebei Medical Journal
