摘要
介绍了腰椎间盘突出后重吸收的时间特点及其与分型的关系,并论述了腰椎间盘突出后重吸收的发生机制,包括炎性细胞吞噬作用、自身免疫反应、血管化、基质金属蛋白酶合成减少、脱水及血肿的吸收、生长因子与细胞因子的影响等,另外论述了中医药对此现象的认识。认为腰椎间盘突出后重吸收现象为中医保守治疗椎间盘突出症的合理性、有效性提供了有力的依据。并提出炎性反应有利于重吸收但同时会造成神经刺激引发疼痛,如何控制、利用炎症是今后研究的一个重要方向。
This paper introduces the chronological characteristic of the resorption after protrusion of lumbar vertebral disc （PLVD） and its relation to different PLVD types. It also discusses the mechanism of the resorption after PLVD, which includes inflammatory cytophagocytosis, autoimmune reaction, vascularization, reduced matrix metalloproteinase synthesis, dehydration and hematoma absorption, influence of growth factors and cytokines, and traditional Chinese medicine （TCM） understanding of this resorption. The author indicates that the resorption after PLVD has provided a powerful prove for the reasonability and effectiveness of TCM conservative therapy in protrusion of the intervertebrai disc, and suggests that inflammatory reaction helps the resorption but causes nerve stimulation leading to pain, so how to control and make use of inflammation is a important research direction in the future.
出处
《南京中医药大学学报》
CAS
CSCD
北大核心
2012年第4期397-400,共4页
Journal of Nanjing University of Traditional Chinese Medicine
基金
江苏省中医药局科技项目(LZ11146)
关键词
椎间盘突出
重吸收
机制
protrusion of the intervertebral disc
resorption
mechanism
