摘要
以L-天冬氨酸为原料,经过甲酯化、氨基保护、水解和还原几步反应合成N-叔丁氧羰基-L-高丝氨酸。与目前已有路线相比,现提出的路线简单且产品纯化较为方便。产物结构经1H-NMR证实。
N-tert-butoxycarbonyl-L-homoserine was prepared via methyl esterification, amino protection, hydrolyzation and reduction of L-aspartic acid. This route is simple and the purification of products is more convenient compared with current synthesis routes. The structure of pr(ntuct was confirmed by ^1H-NMR.
出处
《上海应用技术学院学报(自然科学版)》
2012年第2期137-140,共4页
Journal of Shanghai Institute of Technology: Natural Science