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腹腔镜在治疗胃肠外营养相关性胆汁淤积中的应用 被引量:5

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摘要 目的探讨腹腔镜胆道冲洗术治疗胃肠外营养相关性胆汁淤积(PNAC)的效果。方法回顾性分析2007年11月至2011年3月在我院进行腹腔镜胆道冲洗治疗术的PNAC患儿临床资料,分析患儿围术期情况及手术前后胆汁淤积改善状况。结果本组共13例患儿进行腹腔镜检查,1例术中诊断为胆道闭锁,12例诊断为PNAC的患儿均留置造瘘管,每天生理盐水冲洗,其中6例2周拔出造瘘管,4例4周拔管,1例6周拔管,1例8周拔管。经随访4~44个月,12例患儿均恢复良好。12例患儿初步诊断PNAC时直接胆红素(DBil)水平为(64.9±13.1)μmol/L,总胆汁酸(TBA)水平为(56.4±11.0)μmol/L,内科保守治疗2周后分别为(80.7±19.0)μmol/L和(64.0±16.2)μmol/L,DBil较诊断时升高(P<0.05),TBA无明显变化(P>0.05);术后2周与术前比较,DBil和TBA均明显降低,分别为(44.3±21.5)μmol/L和(35.0±20.1)μmol/L,差异有统计学意义(P<0.001)。结论腹腔镜辅助胆道冲洗治疗PNAC具有操作简单、直观、微创的优点,经胆道冲洗2周以上,治疗PNAC的疗效肯定。
出处 《中国新生儿科杂志》 CAS 2012年第4期254-256,共3页 Chinese Journal of Neonatology
基金 十一五国家科技支撑计划课题( 2006BA105A06)
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