摘要
用涂板菌落计数和激光共聚焦方法观察中药单体黄芪甲苷作用后的鸡异嗜性粒细胞吞噬和杀伤鸡大肠埃希菌O78能力的变化,结果显示,黄芪甲苷在5μg/mL有极显著提高异嗜性粒细胞吞噬大肠埃希菌O78的作用(P<0.01),并且在异嗜性粒细胞发挥杀伤作用12h后有极显著增强其杀伤作用的功效(P<0.01)。结果表明,黄芪甲苷能够提高异嗜性粒细胞吞噬、杀伤大肠埃希菌O78的活性,从而起到增强机体抗病能力,提高机体免疫力的作用。
Studies on the changes of phagocytosis and killing E. coli 078 by avian heterophils regulated with astragaloside IV were conducted. The results showed that astragaloside IV at 5 μg/mL can significantly improve the ability of avian heterophil phagocytosis to E. coli 078 （P〈0.01）, and after 12 h, the killing ability of heterophils was also enhanced（P〈0.01）. The results showed that astragaloside IV can improve the ability of heterophils in phagocytosis and killing E. coli 078 , so as to improve the immune ability.
出处
《动物医学进展》
CSCD
北大核心
2012年第7期27-31,共5页
Progress In Veterinary Medicine
基金
"十一五"国家科技支撑计划(2008BADB4B04-4)
北京农学院兽医学(中医药)北京市重点实验室开放课题(TCVM-201104)
中国农业科学院兰州畜牧与兽药研究所农业部兽用药物创制重点实验室甘肃省新兽药工程重点实验室开放课题(SYSKF2011KT05)
