摘要
目的探讨乳腺癌脑膜转移的MRI表现特点及转移途径。方法回顾性分析21例经临床病理证实的乳腺癌脑膜转移患者的临床及MRI资料。结果 MRI表现:平扫仅3例表现为条片状或结节状异常信号。增强后18例表现为硬脑膜-蛛网膜型,3例为软脑膜-蛛网膜型。12例伴有颅骨骨质破坏,6例伴有脑内转移。乳腺癌脑膜转移途径:11例经邻近颅骨转移灶直接侵犯邻近硬脑膜;5例脑实质表浅部位的转移瘤侵犯邻近硬脑膜;4例经血行直接转移至硬脑膜和(或)柔脑膜,1例经血行转移至脑脊液后播散至柔脑膜。结论 MR增强扫描是乳腺癌脑膜转移的重要检查方法。经颅骨转移瘤侵犯邻近硬脑膜是乳腺癌脑膜转移的主要途径和特点。
Objective To observe MRI features and metastatic routes of meningeal metastases from breast cancer.MethodsTwenty-one patients with meningeal metastases confirmed by clinical data and（or） pathology were retrospectively analyzed.ResultsFlake or meningeal nodules were found in 3 cases on plain MRI.After enhancement,dura-arachnoid enhancement was found in 18 cases,and pia-subarachnoid space enhancement was found in 3 cases.Of 21 patients,skull destruction was found in 12 cases and cerebral metastasis were found in 6 cases.There were four main routes for meningeal involvment of breast cancer： Through adjacent bony metastasis directly involving dura mater（n=11）,through cerebral metastasis directly involving dura mater（n=5）,though hematogenous metastasis to dura mater and（or） leptomeninx（n=4）,while through cerebrospinal fluid spreading to leptomeninx（n=1）.ConclusionContrast-enhanced MR is an important tool for detecting meningeal metastases.Direct involvement of dura mater from adjacent bony metastasis is the main route of meningeal metastasis from breast cancer.
出处
《中国医学影像技术》
CSCD
北大核心
2012年第7期1287-1289,共3页
Chinese Journal of Medical Imaging Technology
关键词
乳腺肿瘤
脑膜肿瘤
肿瘤转移
磁共振成像
Breast neoplasms
Meningeal neoplasms l Neoplasm metastasis
Magnetic resonance imaging
