摘要
目的探讨恶性肿瘤患者发生急性肾功能衰竭(ARF)的原因及防治措施。方法回顾性分析我院2009年8月～2011年10月发生ARF的15例肿瘤患者的临床资料。结果 11例患者因肝多发转移瘤或原发性肝癌肝肾综合征所引起。2例患者因肿瘤压迫输尿管导致肾积水所引起。1例多发性骨髓瘤患者因本周氏蛋白轻链形成的管型引起。1例肺癌患者因应用造影剂后突发ARF。1例胃癌患者因多种原因导致的有效血容量不足引起。结论 ARF是恶性肿瘤的严重并发症,病因复杂,病死率高,治疗上应根据病因进行治疗。对于有高危因素的患者,应高度重视,给予积极补液,改善循环血量,尽早发现ARF的可能,以早期诊断,早期治疗,减少ARF的病死率。
Objective To analysis the cause and means of therapy and prevention of acute renal failure （ARF） in patients with malignant tumors. Methods Clinical data of 15 patients with malignant tumors experienced ARF were retrospectively studied. Results 11 patients suffered ARF because of hepatorenal syndrome. One patients with multiple myeloma had ARF due to cast nephropathy caused by light chain of Bence-Jones protein. One patients with lung cancer experienced ARF induced by contrast media. ARF in 2 patients resulted from obstruction located downstream of the kidneys. ARF in 1 patient with stomach cancer caused by hypovolemia resultingfrom various causes. Conclusions ARF resulting from various causes is a severe complication with high mortality in advanced tumors. The therapy based on cause is crucial to treat ARF. Maintaining adequate circulating volume in patients of high risk factors, early diagnosis and early treatment may reduce mortality caused by ARF.
出处
《西部医学》
2012年第7期1322-1324,共3页
Medical Journal of West China
