新型调脂药胆固醇酯转移蛋白抑制剂的研究进展
被引量:2
摘要
目前冠状动脉粥样硬化性心脏病(简称冠心病),特别是由急性心肌梗死(acutemyocardialinfarction,AMI)导致的心源性死亡,依旧是威胁人类健康的重大公共卫生问题。根据美国心脏病协会(AmericanHeartAssociation,AHA)的估计,美国2007年因冠心病导致的死亡人数高达406351人,约占人群死亡率的1/6。在中国,心脑血管疾病也亦成为中国居民的头号健康杀手。
出处
《中华临床医师杂志(电子版)》
CAS
2012年第13期250-252,共3页
Chinese Journal of Clinicians(Electronic Edition)
参考文献36
-
1Roger VL, Go AS, Lloyd-Jones DM, et at. Heart disease and stroke sta- tistics-2011 update:A report from the American Heart Association. Cir- culation, 2010,123 : e 18-e209. 被引量:1
-
2He J, Gu D, Wu X, et at. Major causes of death among men and women in china. N Engl J Med,2005,353:1124-1134. 被引量:1
-
3Yell RW, Sidney S, Chandra M, et el. Population trends in the inci- dence and outcomes of acute myocardial infarction. N Engl J Med, 2010,362:2155-2165. 被引量:1
-
4Vale N, Nordmann AJ, Schwartz GG, et al. Statins for acute coronary syndrome. Cochrane Database Syst Rev ,2011 : CD006870. 被引量:1
-
5Seehusen DA. Statins for primary cardiovascular prevention. Am Fam Physician, 2011,84 : 767-768. 被引量:1
-
6Chan PS, Nallamothu BK, Gurul HS, et al. Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery disease. Circulation ,2007,115:2398-2409. 被引量:1
-
7Arsenault B J, Lemieux I,Despres JP, ct el. HDL particle size and the risk of coronary heart disease in apparently healthy men and women : The EPIC-Norfolk prospective population study. Atherosclerosis ,2009, 206 : 276 -281. 被引量:1
-
8Hausenloy DJ,Yellon DM. Targeting residual cardiovascular risk : Rai- sing high-density lipoprotein cholesterol levels. Heart, 2008, 94 : 706-714. 被引量:1
-
9Heinecke J. HDL and cardiovascular disease risk-time for a new ap- proach? N Engl J Med ,2011,364 : 170-171. 被引量:1
-
10Singh IM, Shishehbor MH, Ansell BJ. High-density lipoprotein as a therapeutic target:a systematic review. JAMA ,2007,298:786-798. 被引量:1
二级参考文献11
-
1Khan SQ,,Quinnn P,Davies JE,et al.N-terminal pro-B-type natriuretic peptide is better than TIMI risk score at predicting death after acute myocardial infarction. Heart . 2008 被引量:1
-
2Worster A,Balion CM,Hill SA, et al.Diagnostic accuracy of BNP and NT-proBNP in patients presenting to acute care settings with dyspnea:a systematic review. Clinical Biochemistry . 2008 被引量:1
-
3Woodard GE,Rosado JA.Recent advances in natriuretic peptideresearch. Journal of Cellular and Molecular Medicine . 2007 被引量:1
-
4Toth PP,,Davidson MH.Therapeutic interventions targeted atthe augmentation of reverse cholesterol transport. Current Opinion in Cardiology . 2004 被引量:1
-
5Lavie CJ,,Milani RV.Shedding Light on High-Density Lipopro-tein Cholesterol:The Post-ILLUMINATE Era. Journal of the American College of Cardiology . 2008 被引量:1
-
6Tang WH,Steinhubl SR,Van Lente Fet al.Risk stratification for patients undergoing nonurgent percutaneous coronary intervention using B-type natriuretic peptide:a clop idogrel for the reduction of events during observation (CREDO)substudy. American Heart Journal . 2007 被引量:1
-
7Iamendola C.Hypertriglyceridemia and low High-density lipoprotein risks for coronary artery disease. Journal of Cardiovascular Nursing . 2001 被引量:1
-
8Grundy SM,Cleeman Jl,Daniels SR, et al.Diagnosis and management of the metabolic syndrome:an American Heart Association/National Heart, Lung, and Blood Institute scientific statement:Executive Summary. Crit Pathw Cardiol . 2005 被引量:1
-
9陈少敏,郭丽君,高炜.高密度脂蛋白胆固醇对冠状动脉粥样硬化的影响[J].临床心血管病杂志,2008,24(3):223-225. 被引量:18
-
10涂颉洪,戴月.急性心肌梗死患者经皮冠状动脉介入治疗前后脑利钠肽水平的变化及其意义[J].国际内科学杂志,2008,35(12):688-689. 被引量:3
同被引文献57
-
1高炜,李子健.高密度脂蛋白胆固醇与动脉粥样硬化——高密度脂蛋白胆固醇是“好”胆固醇?[J].中国医学前沿杂志(电子版),2011,3(5):1-3. 被引量:1
-
2张峻,陈纪林,顾晴,关婷,陈曦.阻断CD40-CD40配体系统对动脉粥样硬化的影响[J].中国动脉硬化杂志,2006,14(2):119-122. 被引量:18
-
3徐柏玲.胆固醇酯转移蛋白小分子抑制剂的研究进展[J].中国药物化学杂志,2007,17(6):395-402. 被引量:4
-
4Ridker PM. LDL Cholesterol:controversies and future therapeutic directions [J]. Lancet, 2014, 384(9943): 607-617. 被引量:1
-
5Chapman MJ, Ginsberg HN, Amarenco P, et al. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management[J]. Eur Heart J, 2011, 32(11): 1345-1361. 被引量:1
-
6Tenenbaum A, Klempfner R, Fisman EZ. Hypertriglyceridemia: a too long unfairly neglected major cardiovascular risk factor[J]. Cardiovasc Diabetol, 2014, 13(159): 1-10. 被引量:1
-
7Sawar N, Danesh J, Eiriksdottir G, et al. Triglycerides and the risk of coronary heart disease: 10158 incident cases among 262525 participants in 29 Western prospective studies[J]. Circulation, 2007, 115(4): 450-458. 被引量:1
-
8Nordestgaard BG, Benn M, Schnohr P, et al. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women[J]. JAMA, 2007, 298(3): 299-308. 被引量:1
-
9Freiberg JJ, Tybjaerg-Hansen A, Jensen JS, et al. Nonfasting triglycerides and risk of ischemic stroke in the general population[J]. JAMA, 2008, 300(18): 2142-2152. 被引量:1
-
10Varbo A, Benn M, Tybjaerg-Hansen A, et al. Remnant cholesterol as a causal risk factor for ischemic heart disease[J]. J Am Coll Cardiol, 2013, 61(4): 427-436. 被引量:1
二级引证文献14
-
1王桂苹,刘晓堃,韩全乐,张琦.餐后高甘油三酯血症与糖尿病患者的冠状动脉病变程度关系的研究[J].糖尿病新世界,2016,19(2):85-87.
-
2蔡永国,杨志宏,邓文,郑京华.吡格列酮干预前后肥胖大鼠血清甘油三酯水平的研究[J].菏泽医学专科学校学报,2016,28(4):11-12.
-
3徐名一.高脂血症中医治未病思想防治研究进展[J].内蒙古中医药,2018,37(1):81-82. 被引量:2
-
4林龙齐.眼底动脉硬化程度对冠状动脉粥样硬化性心脏病的评估价值[J].中国医学创新,2018,15(21):31-33. 被引量:1
-
5陈银华,徐晓峰,吴磊磊.胆固醇酯转运蛋白抑制剂升高高密度脂蛋白胆固醇的研究进展[J].医学综述,2018,24(17):3356-3360. 被引量:4
-
6李萍,原昌军,孙一卿.“和法”治疗难治性高脂血症的机理探讨[J].现代中医药,2019,39(3):76-78.
-
7王宏涛,卫聪,苏鹏,杨杰,乔博灵.杜仲油软胶囊对模型大鼠血脂水平的调节作用[J].中国药业,2019,28(16):20-22. 被引量:3
-
8姬胭月,白春林.高三酰甘油血症与冠心病关系的研究进展[J].中西医结合心脑血管病杂志,2020,18(23):3992-3997. 被引量:2
-
9杨丽涛,刘银路,毕萃萃,魏芬芬,张波,王京钟.海豹油对高脂血症大鼠和正常大鼠血脂的影响[J].中国油脂,2021,46(3):74-79. 被引量:2
-
10曾艳,巩红飞.庆阳地区2型糖尿病患者营养风险调查及其影响因素分析[J].甘肃科技,2021,37(19):144-147. 被引量:2
-
1韩献华,武峰.胆固醇酯转移蛋白抑制剂的开发及研究进展[J].中国临床药理学杂志,2016,32(4):382-384. 被引量:5
-
2孟立平,池菊芳,郭航远.胆固醇酯转移蛋白抑制剂的作用机制及研究进展[J].浙江医学,2015,37(17):1478-1481.
-
3刘晓婷,阿丽塔,张玢,孙涛涛,许培扬,唐小利.胆固醇酯转移蛋白抑制剂开发[J].世界临床药物,2013,34(7):423-426. 被引量:2
-
4攸竹.家庭5大“毒品”聚集地[J].中国保健营养,2006(11):28-29.
-
5闫丽荣,李一石.调节高密度脂蛋白胆固醇的药物研究进展[J].中国新药杂志,2013,22(15):1768-1773. 被引量:1
-
6嘉勉.Losartan可降低糖尿病患者突发心源性死亡风险[J].中华医学信息导报,2003,18(17):5-5.
-
7吴晴,周小寒.低累积量阿霉素致心源性死亡二例报告分析[J].实用癌症杂志,1996,11(2):136-136. 被引量:1
-
8杜雪,张丽华,乌汉毕力格,张海波,李静,蒋立新.胆固醇酯转移蛋白抑制剂Anacetrapib的研究进展[J].心血管病学进展,2013,34(6):760-766. 被引量:5
-
9邓皓月,陈明.升高高密度脂蛋白胆固醇药物的研究进展[J].心血管病学进展,2016,37(3):258-262. 被引量:2
-
10胆固醇酯转移蛋白抑制剂Anacetrapib Ⅲ期临床试验取得积极结果[J].中国执业药师,2011,8(2):54-54.