期刊文献+

上皮细胞黏附分子与肝癌诊断的研究进展 被引量:3

Research advances of epithelial cell adhesion molecule in liver cancer and its diagnostic role
原文传递
导出
摘要 近年来随着各种肿瘤标志物的相继出现,上皮细胞黏附分子(EpCAM)作为肿瘤标志物有望成为提高肝癌有效诊断率的新指标。笔者就文献所述归纳了该标志物的生物学特征及其在肝脏发育和肝癌中的表达,以及在临床诊断中应用的现状和前景。 A variety of tumor markers have been identified over the past years,among which,epithelial cell adhesion molecule(EpCAM) is expected to become a new diagnostic factor for improving the detection rate of liver cancer.Based on reports in the literature,this paper summarizes the biological characteristics of EpCAM and its expression characteristics in liver development and liver cancer,as well as the current status and prospects of its application in clinical diagnosis.
出处 《中国普通外科杂志》 CAS CSCD 北大核心 2012年第7期873-876,共4页 China Journal of General Surgery
关键词 肝肿瘤/诊断 上皮细胞黏附分子 综述文献 Liver Neoplasms/Diag Epithelial Cell Adhesion Molecule Review
  • 相关文献

参考文献32

  • 1杨秉辉,丛文铭,周晓军,陈孝平,杨甲梅,樊嘉,王建华,杨仁杰,李槐,蒋国梁,曾昭冲,陈敏华,陈敏山,梁萍,吕明德,罗荣城,刘鲁明,秦叔逵,叶胜龙,吴孟超,汤钊猷,孙燕,管忠震.原发性肝癌规范化诊治专家共识[J].临床肿瘤学杂志,2009,14(3):259-269. 被引量:313
  • 2Tang ZY, Ye SL, Liu YK, et al. A decade's studies on metastasis of hepatocellular carcinoma[J]. J Cancer Res Clin Oncol, 2004, 130(4):187-196. 被引量:1
  • 3Herlyn M, Steplewsld Z, Herlyn D, et al. Colorectal carcinoma- specific antigen : detection by means of monoclonal antibodies[J]. Proc Natl Acad Sci U S A, 1979, 76(3):1438-1442. 被引量:1
  • 4Calabrese G, Crescenzi C, Morizio E, et al. Assignment of TACSTD1 (alias TROP1,M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2,M1S1) to human chromosome lp32 by in situ hybridization[J]. Cytogenet Cell Genet, 2001, 92(1- 2):164-165. 被引量:1
  • 5Balzar M, Briaire-de Bruijn IH, Rees-Bakker HA, et al. Epidermal growth factor-like repeats mediate lateral and reciprocal interactions of EpCAM molecules in homophilic adhesiom[J]. Mol Cell Biol, 2001, 21(7):2570-2580. 被引量:1
  • 6Litvinov SV, Velders MP, Bakker HA, et al. EpCAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule[J]. J Cell Biol, 1994, 125(2):437-446. 被引量:1
  • 7Schiech] H, Dohr G. lmmunohistochemical studies of the distribution of a basolateral-membrane protein in intestinal epithelial cells (GZ1-Ag) in rats using monoclonal antibodies[J]. Histochem Cell Biol, 1987, 87(5):491--498. 被引量:1
  • 8Balzar M, Winter MJ, de Boer CJ, et al. The biology of the 17-1A antigen (EpCAM) [J]. J Mol Med, 1999, 77(10):699-712. 被引量:1
  • 9Munz M, Kieu C, Mack B, et al. The carcinoma-associated antigen EpCAM npregulates c-myc and induces cell proliferation[J]. Oncogene, 2004, 23(34):5748-5758. 被引量:1
  • 10Osta WA, Chen Y, Mikhitarian K, et al. EpCAM is overexpressed in breast cancer and is a potentia| target for breast cancer gene therapy[J]. Cancer Res, 2004, 64(16):5818-5824. 被引量:1

共引文献312

同被引文献14

引证文献3

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部