摘要
目的:探讨不同氟暴露情况下男性人群不育情况的差异。方法:对高氟区组94例和低氟区组1 1 4例男性人群与氟暴露相关的生活居住环境、饮食情况、生育情况等进行调查,并分析比较两组人群生活习惯、氟暴露情况、生育情况等的差异。结果:高氟区组在经常用煤、喜爱喝茶、氟斑牙程度、不育率等方面显著高于低氟区组(P<0.05),而在炉灶改良、使用含氟牙膏等方面显著低于低氟区组(P<0.05);多因素Logistic回归显示"调查对象来自高氟区"和"使用未改良炉灶"对男性不育的影响有统计学意义(P<0.05)。结论:高氟区组在煤烟型氟暴露和不育情况方面均比低氟区组更严重,提示长期高氟暴露是不育的危险因素,可致男性人群不育的风险升高。
Objectlve：To explore the differences of male infertility in different fluorine exposure populations. Methods：Villages were divided into high-fluorine-region group （n = 94） and low-fluorine-region group （n = 114）. Their living situations,diet,fertility and other fluorine exposure related aspects were collected and compared between two groups. Results：Compared with low-fluorine- region group,it was significantly higher in the frequency of using coal and drinking tea,degree of dental fluorosis,and rate of infertility（P 〈 0.05）,while significantly lower in the use of improved stoves and fluorine toothpaste in high-fluorine-region group（P 〈 0.05）. The factors of ＂survey objects from high-fluorine region＂ and ＂stove unimprovement＂ significantly affected on male infertility in multiple Logistic regression （P 〈 0.05）. Conclusion： Coal-burning-type fluorine exposure and the incidence rate of infertility in highfluorine-region group was more serious than low-fluorine-region group,which suggested that long-term fluorine exposure was a risk factor of infertility, which could increase the risk of male infertility.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2012年第7期1024-1028,共5页
Journal of Nanjing Medical University(Natural Sciences)
基金
贵州省科技厅基金(黔科合J字[2009]2322号)
贵州省科技厅
遵义医学院
遵义市科技局联合基金(黔科合J字LKZ[2010]32号)
贵州省卫生厅优秀医学青年科技人才基金(gzwkj2010-2-001)
关键词
不育
男性
氟暴露
infertility
male
fluorine exposure
