摘要
目的研究结核分枝杆菌荧光定量聚合酶链反应(TB-PCR)检测技术及胸膜活检在诊断结核性渗出性胸膜炎的临床价值。方法 282例确诊为结核性渗出性胸膜炎患者行胸腔穿刺抽液术,胸液送检TB-PCR,同时行针刺胸膜活检,胸膜活检组织标本送检病理检查,比较两种检测方法的阳性率。结果 TB-PCR检测阳性率55.3%,明显高于胸膜活检阳性率37.9%,差异有高度统计学意义(P<0.01),聚合酶链式反应检测明显优于胸膜活检。两种方法联合检出阳性率为64.2%。结论 TB-PCR是目前针对结核分枝杆菌检测阳性率较高的方法;联合胸膜活检,可提高对结核性渗出性胸膜炎的早期诊断。
Objective To study the clinical value of Mycobacterium Tuberculosis Fluorescence Quantitative （TB-PCR） and pleura biopsy in detection of tuberculous exudative pleurisy. Methods 282 tuberculous exudative pleurisy patients were operated paracentesis. The pleura1 effusions were detected by TB-PCR and pleura biopsy needle, and the pleura biopsy tissue samples were examined by pathology. Then positive rates of these two examination methods were compared. Results The positive rate in TB-PCR was 55.3%, much higher than 37.9% in pleura biopsy （P 〈 0.01）, with significant statistic differences, which showed fluorescence quantitative PCR was better than pleura biopsy. The positive rate of two methods joining together was 64.2%. Conclusion TB-PCR is a method of detecting mycobacterium tuberculosis with a comparatively high positive rate recently. Combined with pleura biopsy, it can improve the early diagnosis of tuberculous exudative pleurisy.
出处
《中国现代医生》
2012年第18期33-34,36,共3页
China Modern Doctor
