摘要
目的观察米索前列醇不同给药途径对产后出血的临床效果。方法选择2009年10月～2011年10月于我院进行分娩的124例产妇为研究对象,所有产妇均已被判断为高危或先兆产后出血,随机分为实验组和对照组,实验组使用缩宫素和米索前列醇直肠给药,对照组仅使用缩宫素。结果两组产妇术中出血量无统计学意义(P>0.05),实验组术后2 h、24 h出血量明显少于对照组(P<0.01),两组产妇均无明显不良反应。两组产妇术后收缩压和舒张压比较均无统计学意义(P>0.05)。结论在常规使用缩宫素的基础上采用直肠给药能够有效预防产后出血,且其安全性较高,值得临床广泛使用。
Objective To compare the clinical effect of misoprostol administered by different routes for preventing postpar- tum hemorrhage. Methods Selected 124 cases maternal deliveried from October 2009 to October 2011 in our hospital as study object,all the women had been judged as high risk or threatened post-partum hemorrhage,whom were randomly di- vided into experimental and control groups,experimental group used oxytocin and misoprostol rectally,the control group used only oxytocin. Results There were no significant differences in maternal blood loss during delivery between two groups （P 〉 0.05）;Mter 2 h and 24 h, the experimental group were significantly less than the control group in blood loss （P 〈 0.01）,two groups mothers had no obvious adverse reactions and the systolic and diastolic blood pressure were not statis- tically different （P 〉 0.05）. Conclusion Rectal route of misoprostol to prevent postpartum hemorrhage on the basis of the use o.f Oxytocin can be effective in preventing postpartum hemorrhage,and it has high security,which is worthy of widespread use.
出处
《中国现代医生》
2012年第16期130-131,共2页
China Modern Doctor
关键词
米索前列醇
直肠给药
口服给药
产后出血
Misoprostol
Rectal administration
Oral administration
Postpartum hemorrhage
