摘要
目的 :采用脑电双频谱指数 (BIS)评价依托咪酯乳剂在老年人麻醉诱导时的深度及循环的变化。方法 :2 0例ASAⅠ～Ⅱ级腹腔镜胆囊切除术患者 ,年龄大于 60岁 (n =1 0 )为老年组 ,小于 60岁 (n =1 0 )为对照组。麻醉诱导用药为芬太尼 2ug/kg、依托咪酯 0 3mg/kg、阿曲库铵 0 5mg/kg。结果 :老年组最低BIS为 43 1± 6 4,对照组为 38 4± 4 7,无显著差异。达最低BIS所需时间老年组为 43 5± 7 4秒 ,对照组为 35 6± 8 1秒 (P <0 0 5) ;老年组用药前后的BP、HR稳定 ,对照组心率明显下降 (P <0 0 5)。结论
Object:To evaluate the changes of BIS and circulation following induction of anesthesia with emulsion of etomidate in aged patients.Method:Twenty patients(ASAⅠ Ⅱ) undergoing elective cholecystectomy were divided into groups A(age>60, n= 10) and C(age<60, n= 10).Fentanyl 2μg/kg etomidate 0 3mg/kg and atracurium 0 5mg/kg were administered i.v.for anesthesia induction.Result:The lowest BIS was 43 1±6 4 in group A and 38 4±4 7 in group C( P> 0 05).The onset time of lowest BIS was 43 5±7 4s in group A and 35 6±8 1s in group C( P< 0 05).The BP and HR of group A was stable,while HR was significantly decreased in group C( P< 0 05).Conclusion:Induction of anesthesia with emulsion of etomidate is safe in aged patients.
出处
《临床麻醉学杂志》
CAS
CSCD
2000年第4期184-185,共2页
Journal of Clinical Anesthesiology
