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微小RNA调控T淋巴细胞分化的研究进展 被引量:1

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摘要 T细胞是重要的免疫效应细胞,其分化将影响特异性免疫应答的方向和强度。深入研究和阐明T细胞分化过程中的调控机制,对于肿瘤以及自身免疫病的防治具有重要价值。微小RNA(microRNA,miR)是一类长度为18~25核苷酸的内源性短链非编码RNA分子,可以通过与靶基因的特异性互补作用来降解mRNA或者抑制其翻译,并在特定条件下上调靶基因的转录和翻译。
作者 钟国成 朱波
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2012年第6期569-572,共4页 Chinese Journal of Immunology
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