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心脏死亡供体肝移植的临床应用进展 被引量:2

Liver transplantation using donation after cardiac death donors
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摘要 供肝短缺是目前肝移植发展的全球性难题。近年来,心脏死亡供体肝移植数量明显增加,因此,心脏死亡供体可能是拓展肝脏捐献来源的重要途径。较高的胆道并发症、原发性移植肝无功能、肝动脉栓塞是影响心脏死亡供体肝移植术后生存质量的重要因素,缩短热缺血时间、体外膜肺技术、体外低温机器灌注是改善心脏死亡供体肝移植术后生存质量的主要措施。 The shortage of liver organ donor is the barrier to the development of liver transplantation. In the past recent years, the usefulness of the donation after cardiac death donor has increased significantly. So the donor after cardiac death may be the important way to expand the liver organ donor pool. The high incidence of the biliary com- plication, primary non function and the arterial thrombosis may the most important effectors on the survival outcome of the recipients accepted liver after cardiac death. Reducing warm ischemia time, extracorporeal membrane oxygenation and ex vivo hypothermic machine perfusion may be the ways to improve the life quality of the liver donor after cardiac death and the survival outcome of the recipients.
出处 《国际外科学杂志》 2012年第6期420-423,共4页 International Journal of Surgery
关键词 心脏死亡供体 肝脏移植 生存质量 体外膜肺技术 机械灌注 Donor after cardiac death Liver transplantation Survival outcome Extracorporeal membrane oxygenation Machine perfusion
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